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引用本文:杨东方,胡云飞,丁倩倩,周建理.密蒙花的化学成分及质量控制方法研究进展[J].中国现代应用药学,2019,36(22):2870-2875.
YANG Dongfang,HU Yunfei,DING Qianqian,ZHOU Jianli.Research Progress on Chemical Constituents and Quality Control Methods of Buddleja Officinalis Maxim.[J].Chin J Mod Appl Pharm(中国现代应用药学),2019,36(22):2870-2875.
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密蒙花的化学成分及质量控制方法研究进展
杨东方1, 胡云飞2,3,4, 丁倩倩4, 周建理2,3
1.山西药科职业学院, 太原 030031;2.安徽中医药大学, 合肥 230031;3.亳州学院, 安徽 亳州 236800;4.安徽新华学院, 合肥 230088
摘要:
对密蒙花化学成分、质量评价体系及控制方法研究进展做系统分析,为进一步完善密蒙花的质量评价体系提供参考与依据。对大量国内外相关文献进行查阅、比较与分析,并对其进行归纳与综述。密蒙花中化学成分丰富,其中黄酮类、苯乙醇苷类、挥发油类和三萜类等为主要活性物质;其质量控制方法涉及传统的性状鉴别、显微鉴别、理化鉴别及光谱法、色谱法等多种技术。其质量控制方法虽多,但并不完善,面对掺伪造假、等级评价模糊等问题,建立一套灵敏度高及专属性强的密蒙花质量评价体系显得尤为重要。
关键词:  密蒙花  化学成分  质量控制  质量标准
DOI:10.13748/j.cnki.issn1007-7693.2019.22.026
分类号:R284.1
基金项目:国家质量监督检验检疫总局科技计划项目(2015QK098);山西省高等学校科技创新项目(20171118);安徽省公益性研究联动计划项目(1604f0804005);亳州市科技计划项目(BK2015009)
Research Progress on Chemical Constituents and Quality Control Methods of Buddleja Officinalis Maxim.
YANG Dongfang1, HU Yunfei2,3,4, DING Qianqian4, ZHOU Jianli2,3
1.Shanxi Pharmaceutical Vocational College, Taiyuan 030031, China;2.Anhui University of Traditional Chinese Medicine, Hefei 230031, China;3.Bozhou University, Bozhou 236800, China;4.Anhui Xinhua University, Hefei 230088, China
Abstract:
To provide reference and basis for improving the quality evaluation system of Buddleja officinalis Maxim., the research progress of chemical composition, quality evaluation system and control method of Buddleja officinalis Maxim. are systematically analyzed. A large number of domestic and foreign related references are reviewed, compared and analyzed, and summarized and reviewed. There are abundant chemical constituents in Buddleja officinalis Maxim., flavonoids, phenylethanol glycosides, volatile oils and triterpenoids were the main active substances. The quality control methods involved traditional character identification, microscopic identification, physical and chemical identification, spectroscopy, chromatography and other techniques. Although there are many quality control methods, it is not perfect. In the face of the problems of adulteration and fraud, and the evaluation of grades, it is particularly important to establish a set of high-sensitivity and special-specific quality evaluation system of Buddleja officinalis Maxim..
Key words:  Buddleja officinalis Maxim.  chemical composition  quality control  quality standard
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