| 引用本文: | 车鑫,刘珂,许卉,刘军锋.丹酚酸A中树脂残留溶剂的测定[J].中国现代应用药学,2010,27(9):854-856. |
| .Determination of Residues from Macroporous Adsorbing Resins in Salvianolic Acid A[J].Chin J Mod Appl Pharm(中国现代应用药学),2010,27(9):854-856. |
|
|
| 摘要: |
| 目的 建立丹酚酸A中树脂残留溶剂正己烷、甲基环己烷、苯、甲苯、二甲苯、苯乙烯、二乙烯苯的测定方法。方法 采用顶空毛细管气相色谱法进行测定，色谱柱为HP–1701毛细管柱；程序升温，初始温度为40 ℃，保持3 min后，以8 ℃·min-1升温至140 ℃；FID检测器。结果 线性关系良好(r>0.999)，回收率在96.53%~99.32%之间。结论 本法简便、准确，适用于丹酚酸A中树脂残留溶剂的测定。 |
| 关键词: 丹酚酸A 残留溶剂 气相色谱法 |
| DOI： |
| 分类号: |
| 基金项目: |
|
| Determination of Residues from Macroporous Adsorbing Resins in Salvianolic Acid A |
|
CHE Xin1 LIU Ke1* XU Hui1 LIU Junfeng2
|
| Abstract: |
| OBJECTIVE To establish a method for detecting the residues, including hexane, methylcyclohexane, benzene, toluene, xylene, styrene, diethylbenzene divinybenzene, from macroporous adsorptions resin in salvianolic acid A. METHODS Headspace GC was adopted using an HP-1701 capillary column and hydrogenflame ionization detector. The initial temperature was 40 ℃ maintained for 3 min and then raised (8 ℃·min-1) to 140 ℃. RESULTS There was favorable linearity relation between peak area and concentration in the observed concentration range(r>0.999). The average recovery was in the range of 96.53%–99.32%. CONCLUSION The method is simple, accurate and specific. It can be used for the determination of residues from macroporous adsorbing resins in salvianolic acid A. |
| Key words: salvianolic acid A residues GC |
