| 引用本文: | 王法琴1,2，李平1*，魏琴1，戴亚妮1,2.凹凸棒对中药水煎液中绿原酸及牛蒡苷的吸附作用考察[J].中国现代应用药学,2009,(12):991-995. |
| WANG Faqin1,2, LI Ping1*, WEI Qin1, DAI Yani1,2.Adsorptive Effect of the Attapulgite on Chlorogenic Acid and Arctiin in Decoction[J].Chin J Mod Appl Pharm(中国现代应用药学),2009,(12):991-995. |
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| 摘要: |
| 目的 考察凹凸棒作为吸附澄清剂，对中药水煎提取液中有效成分绿原酸与牛蒡苷的吸附影响和对无效成分的吸附去除作用。方法 以绿原酸及牛蒡苷的含量、浸出物含量和溶液澄清度为指标，分别用不同浓度的普通凹凸棒石、酸化凹凸棒石以及自然放置方法处理中药金银花、牛蒡子及银翘解毒颗粒水煎提取液，考察普通凹凸棒和酸化凹凸棒对中药水煎液中绿原酸与牛蒡苷的吸附影响以及对无效成分的去除作用。结果 凹凸棒对无效成分具有较明显的吸附清除作用，对绿原酸的保留较好，对牛蒡苷有一定的吸附影响，酸化凹凸棒去除无效成分的效果优于普通凹凸棒。结论 凹凸棒可作为银翘解毒颗粒水煎提取液的吸附澄清剂，尤其是酸化凹凸棒值得作进一步的表面结构修饰研究，以优化其吸附澄清效果。 |
| 关键词: 凹凸棒石 绿原酸 牛蒡苷 吸附澄清剂 |
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| Adsorptive Effect of the Attapulgite on Chlorogenic Acid and Arctiin in Decoction |
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WANG Faqin1,2, LI Ping1*, WEI Qin1, DAI Yani1,2
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| Abstract: |
| OBJECTIVE To study the adsorptive influence of attapulgite as adsorptive clarifier on chlorogenic acid and arctiin in traditional Chinese medicine decoction, and investigate the clarified effect of attapulgite on ineffective components. METHODS Using the contents of chlorogenic acid, arctiin, extracta and clarity of solution as indexes, the water extraction of honeysuckle flower, great burdock achene and yinqiao jiedu granules were treated with different amount acidified and common attapulgite respectively. Further, these adsorptive effects were evaluated. RESULTS Attapulgite had a significant clarified effect on ineffective components, the reservatinon of chlorogenic acid was preferable, and arctiin was adsorpted with low amount. Acidified attapulgite was better than common attapulgite in clearing ineffective compontents. CONCLUSION Attapulgite can be used as adsorptive clarifier in the water extraction of yinqiao jiedu granules, especially, more modification evidences of surface structure about acided attapulgite would be awaited to study. |
| Key words: attapulgite chlorogenic acid arctiin adsorptive clarifier |
