| 摘要: |
| 目的 观察穿心莲滴丸联合金栀洁龈含漱液治疗复发性阿弗他溃疡（recurrent aphthous ulcer，RAU）的疗效。方法 将86位RAU患者随机分为试验组和对照组（n=43），试验组使用穿心莲滴丸联合金栀洁龈含漱液治疗RAU，对照组仅用金栀洁龈含漱液，2组在治疗后的第1，3，5，7和10天观察患者的疼痛程度、溃疡的愈合情况，并进行总有效率的比较。结果 试验组在治疗后第1，3，5和7天的疼痛程度均低于对照组（P<0.05）；试验组溃疡愈合时间小于对照组（P<0.05）；治疗后第1天，2组愈合率（wound healing rate，WHR）无明显差异，治疗后第3天，试验组WHR大于对照组（P<0.05）；试验组总有效率大于对照组（P<0.05）。结论 穿心莲滴丸联合金栀洁龈含漱液能加快RAU愈合，减轻疼痛，缩短病程。 |
| 关键词: 复发性阿弗他溃疡 穿心莲 漱口液 疗效 |
| DOI：10.13748/j.cnki.issn1007-7693.2020.15.017 |
| 分类号:R285.6 |
| 基金项目: |
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| Clinical Observation of Andrographis Dropping Pills Combined with Jinzhijieyin Gargle in the Treatment of Recurrent Aphthous Ulcer |
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YANG Qinqiu
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Suining First People's Hospital, Suining 629000, China
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| Abstract: |
| OBJECTIVE To observe the effect of Andrographis paniculata dropping pills combined with Jinzhijieyin Gargle in the treatment of recurrent aphthous ulcer(RAU). METHODS Eighty six patients with RAU were randomly divided into experimental group and control group(n=43). Treatment of RAU with Andrographis paniculata dropping pills and Jinzhijieyin gargle in the experimental group, the control group only used Jinzhijieyin gargle. On the 1 st, 3 rd, 5 th, 7 th and 10 th day after treatment, the pain degree and ulcer healing were observed and the total effective rate was compared between the two groups. RESULTS The degree of pain in the experimental group was lower than that in the control group on the 1st, 3rd, 5th and 7 th day after treatment(P<0.05). The healing time of ulcer in the experimental group was shorter than that in the control group(P<0.05). On the first day after treatment, there was no significant difference in the healing rate(WHR) between the two groups. On the third day after treatment, WHR in the experimental group was higher than that in the control group(P<0.05). The total effective rate of the experimental group was higher than that of the control group(P<0.05). CONCLUSION Andrographis paniculata dropping pills combined with Jinzhijieyin gargle can accelerate the healing of RAU, relieve pain and shorten the course of disease. |
| Key words: recurrent aphthous ulcer Andrographis paniculata mouthwash curative effect |
