| 引用本文: | 翟耀敏,邱利焱.含原酸酯基团的pH敏感纳米载体在抗肿瘤药物递送中的应用进展[J].中国现代应用药学,2020,37(12):1508-1516. |
| ZHAI Yaomin,QIU Liyan.Application Progress of pH-sensitive Nanocarriers Containing Orthoester Groups for Anti-tumor Drug Delivery[J].Chin J Mod Appl Pharm(中国现代应用药学),2020,37(12):1508-1516. |
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| 摘要: |
| pH敏感型纳米药物载体在癌症治疗方面的研究正受到越来越多的关注，显示出诸多优势和良好的应用前景。已报道的pH敏感型纳米药物载体包括多种类型。本文针对含原酸酯基团的pH敏感纳米药物载体，综述了其近年来的研究进展，并介绍了该类药物载体在抗肿瘤药物递送中的应用。 |
| 关键词: 原酸酯 pH敏感 纳米载体 药物递送 抗肿瘤 |
| DOI：10.13748/j.cnki.issn1007-7693.2020.12.020 |
| 分类号:R94 |
| 基金项目:国家自然科学基金项目（81872825） |
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| Application Progress of pH-sensitive Nanocarriers Containing Orthoester Groups for Anti-tumor Drug Delivery |
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ZHAI Yaomin, QIU Liyan
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Department of Polymer Science and Engineering, Zhejiang University, Hangzhou 310027, China
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| Abstract: |
| At present, pH-sensitive drug nanocarriers are receiving more and more attentions for their unique advantages and potential applications. Various types of pH-sensitive drug nanocarriers have been developed. This paper summarizes the research progress of pH-sensitive drug nanocarriers containing ortho ester groups in the recent years, and introduces their applications in anti-tumor drug delivery. |
| Key words: ortho ester pH-sensitive nanocarrier drug delivery anti-tumor |
