| 引用本文: | 刘利艳,王莹,刘波,徐彭.苜蓿素生物活性研究进展[J].中国现代应用药学,2020,37(6):764-768. |
| LIU Liyan,WANG Ying,LIU Bo,XU Peng.Research Progress on Bioactivity of Tricin[J].Chin J Mod Appl Pharm(中国现代应用药学),2020,37(6):764-768. |
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| 摘要: |
| 苜蓿素为天然黄酮类化合物，广泛存在许多天然可食性植物中，其生物活性主要有抗炎、抗氧化应激、抗过敏、抗肿瘤、抑制微生物生长（巨细胞病毒、利什曼虫和胃肠道线虫）、降血糖和降血脂等作用，且安全性好，可成为新药开发的方向。本文综述近些年国内外文献，对苜蓿素的生物学活性及其作用机制的研究现状作一总结，为新药开发提供理论依据。 |
| 关键词: 苜蓿素 生物活性 新药开发 作用机制 |
| DOI：10.13748/j.cnki.issn1007-7693.2020.06.027 |
| 分类号:R282.7 |
| 基金项目:江西省卫生计生委中医药科研课题（2014A026） |
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| Research Progress on Bioactivity of Tricin |
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LIU Liyan1,2, WANG Ying1, LIU Bo1, XU Peng3
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1.Jiangxi University of Traditional Chinese Medicine, College of Pharmacy, Nanchang 330004, China;2.Department of Pharmacy, Jiangxi Provincial Cancer Hospital, Nanchang 330029, China;3.Jiangxi University of Traditional Chinese Medicine, Laboratory Animal Science and Technology Center, Nanchang 330004, China
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| Abstract: |
| Tricin is a natural flavonoid compound, which is widely found in many natural edible plants. Its biological activities mainly include anti-inflammatory reaction, anti-oxidative stress, anti-allergic, anti-tumor, inhibition of microbial growth(cytomegalovirus, leishmania and gastrointestinal nematodes), hypoglycemic and hypolipidemic effects. It can become the direction of new drug development for its good safety. This paper summarizes the research status of the biological activity and mechanism of tricin in domestic and foreign in recent years and provides a theoretical basis for the development of new drugs. |
| Key words: tricin bioactivity new drug development mechanism |
