| 引用本文: | 洪义东,胡楠,卞宝祥,宋子琰,吴风雷.铜绿假单胞菌注射液抗肿瘤作用及其相关机制的研究进展[J].中国现代应用药学,2019,36(2):256-259. |
| HONG Yidong,HU Nan,BIAN Baoxiang,SONG Ziyan,WU Fenglei.Research Advances in the Mechanisms for Anti-tumor Effect of Pseudomonas Aeruginosa Injection[J].Chin J Mod Appl Pharm(中国现代应用药学),2019,36(2):256-259. |
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| 摘要: |
| 绿假单胞菌注射液（PA-MSHA）是一类用于免疫治疗的生物制剂，在临床应用和基础研究中均表现出良好的抗肿瘤作用。其抗肿瘤作用包括调节免疫、提高化疗药物敏感性和逆转耐药等方面。本文对铜绿假单胞菌注射液抗肿瘤作用及其相关机制研究进展进行综述。 |
| 关键词: 铜绿假单胞菌注射液 肿瘤治疗 免疫 信号通路 耐药 |
| DOI：10.13748/j.cnki.issn1007-7693.2019.02.027 |
| 分类号:R96 |
| 基金项目: |
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| Research Advances in the Mechanisms for Anti-tumor Effect of Pseudomonas Aeruginosa Injection |
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HONG Yidong1,2, HU Nan1, BIAN Baoxiang1, SONG Ziyan1, WU Fenglei1,2
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1.School of Medicine, Jiangsu University, Zhenjiang 212013, China;2.First People's Hospital of Lianyungang, Lianyungang 221000, China
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| Abstract: |
| Pseudomonas aeruginosa injection(PA-MSHA) is a kind of biologics agents for immunotherapy, which demonstrates promising anti-tumor effects in both clinical and basic research. The mechanism of its anti-tumor effects include regulating immunity, increasing the sensitivity of chemotherapy drug and reversing the drug resistance. This review focuses on the research advances in the mechanisms for anti-tumor effect of PA-MSHA injection. |
| Key words: pseudomonas aeruginosa injection tumor therapy immunity signal pathway drug resistance |
