| 引用本文: | 庞露,朱珂,孙亚欣,李国飞,刘立民,朱旭,肇丽梅.临床药师参与伏立康唑治疗方案调整1例并文献复习[J].中国现代应用药学,2018,35(11):1725-1728. |
| PANG Lu,ZHU Ke,SUN Yaxin,LI Guofei,LIU Limin,ZHU Xu,ZHAO Limei.Clinical Pharmacists Participating in the Adjustment of Treatment Regimen of Voriconazole: A Case Report and Literature Review[J].Chin J Mod Appl Pharm(中国现代应用药学),2018,35(11):1725-1728. |
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| 临床药师参与伏立康唑治疗方案调整1例并文献复习 |
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庞露1, 朱珂2, 孙亚欣1, 李国飞1, 刘立民1, 朱旭1, 肇丽梅1
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1.中国医科大学附属盛京医院, 药学部, 沈阳 110004;2.中国医科大学附属盛京医院, 血液科, 沈阳 110004
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| 摘要: |
| 目的 探讨临床药师参与1例使用伏立康唑治疗肺部真菌感染患者的治疗方案调整，为复杂患者的个体化用药提供信息支持。方法 临床药师利用治疗药物监测及基因检测作为技术支持，药学指南及文献作为信息支持，为临床医师提供参考意见，改善治疗效果。结果 治疗过程中，临床药师根据患者情况提出用药调整建议，与医师共同制定个体化治疗方案并随时调整，节省了医疗费用，提高了患者的依从性。结论 临床工作中，部分患者存在治疗疗程长、联合用药复杂的问题，治疗药物监测、基因检测等技术的应用，为临床个体化用药提供了技术保障，而临床药学人员的参与，也为个体化用药的逐步完善提供了一定的支持。 |
| 关键词: 伏立康唑 药物监测 基因检测 个体化用药 临床药师 |
| DOI：10.13748/j.cnki.issn1007-7693.2018.11.029 |
| 分类号:R969.4 |
| 基金项目: |
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| Clinical Pharmacists Participating in the Adjustment of Treatment Regimen of Voriconazole: A Case Report and Literature Review |
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PANG Lu1, ZHU Ke2, SUN Yaxin1, LI Guofei1, LIU Limin1, ZHU Xu1, ZHAO Limei1
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1.Department of Pharmacy, Shengjing Hospital of China Medical University, Shenyang 110004, China;2.Department of Hematology, Shengjing Hospital of China Medical University, Shenyang 110004, China
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| Abstract: |
| OBJECTIVE To adjust the treatment regimen, the clinical pharmacist involved in the treatment of one patient with pulmonary fungal infection treated with voriconazole, who provide information support for the individualized medication of complicated patients. METHODS Clinical pharmacist used therapeutic drug monitoring and genetic testing as technical support, pharmacy guidelines and literature as information support to provide suggestion for clinicians and improve the therapeutic effect. RESULTS During the course of treatment, the clinical pharmacist recommended adjustments for medication according to the patient's condition, and formulated individualized treatment plans with clinicians to save medical expenses and improve patient compliance. CONCLUSION Some patients have long treatment course and complex combination of drugs in clinical practice. Therapeutic drug monitoring, genetic testing and other technologies can provide technical support for individualized medication. And the participation of clinical pharmacist also can provide some support for individualized medication. |
| Key words: voriconazole drug monitoring genetic testing individualized drug administration clinical pharmacist |
