| 引用本文: | 侯齐书,叶继锋,朱光辉,王增寿.新生儿常见超说明书用药的合理性探讨[J].中国现代应用药学,2018,35(5):760-763. |
| HOU Qishu,YE Jifeng,ZHU Guanghui,WANG Zengshou.Discussion on the Rationality of Common Off-label Use in Neonates[J].Chin J Mod Appl Pharm(中国现代应用药学),2018,35(5):760-763. |
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| 摘要: |
| 目的 分析新生儿科常见超说明书用药的合理性，为保障新生儿安全合理用药提供依据。方法 收集2016年8月-2017年7月新生儿科住院患儿用药医嘱，对其中常见的超说明书用药情况进行合理性分析与评价。结果 超说明书用药的存在不可避免，应根据循证医学证据强度对超说明书用药合理性进行评价。结论 临床药师应参与药物超说明书用药的规范化管理，积极寻找医学证据，为临床医师提供科学合理的用药参考。 |
| 关键词: 新生儿 超说明书用药 用药合理性 |
| DOI：10.13748/j.cnki.issn1007-7693.2018.05.029 |
| 分类号:R969.3 |
| 基金项目:温州市公益性科技计划项目（Y20170698） |
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| Discussion on the Rationality of Common Off-label Use in Neonates |
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HOU Qishu, YE Jifeng, ZHU Guanghui, WANG Zengshou
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The 2nd Affiliated Hospital & Yuying Children's Hospital of Wenzhou Medical University, Wenzhou 325000, China
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| Abstract: |
| OBJECTIVE To discuss the rationality of common off-label use in neonates, and to provide a reference for neonates safety and rational administration.METHODS Medication orders in neonatal department were collected from August 2016 to July 2017, and the rationality of common off-label use evaluated.RESULTS Off-label use was inevitably, which should be evaluated on the basis of analysis on the presence of evidence-based.CONCLUSION Clinical pharmacists shall participate in the standard management of off-label use, seek medical evidence actively, and provide scientific and reasonable suggestions to clinicians. |
| Key words: neonate off-label use rationality of administration |
