| 引用本文: | 赵杰,张冠东,薛智民,杨钰,高燕飞,韩燕,赵瑞玲.更昔洛韦儿童用药安全失效模式筛选及分析[J].中国现代应用药学,2018,35(5):770-773. |
| ZHAO Jie,ZHANG Guandong,XUE Zhimin,YANG Yu,GAO Yanfei,HAN Yan,ZHAO Ruiling.Screening and Analysis of Safety Failure Modes of Ganciclovir in Pediatric Drug Therapy[J].Chin J Mod Appl Pharm(中国现代应用药学),2018,35(5):770-773. |
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| 摘要: |
| 目的 分析更昔洛韦用药安全中的风险点，制定用药安全防范策略。方法 利用失效模式与效果分析法，通过文献检索、问卷调查、实地考察等步骤，寻找更昔洛韦儿童用药过程中的失效模式。结果 通过风险优先级数评分，共获5项需立即干预的更昔洛韦用药风险点，并针对这些风险点制定防范策略。结论 更昔洛韦在儿科临床使用的各个环节仍有许多用药风险存在。我国关于儿童合理用药的法律、法规、部门规章、规定甚少，关于保障和促进儿童合理用药的政策有待落实和实施。 |
| 关键词: 更昔洛韦 儿童 失效模式与效果分析 |
| DOI：10.13748/j.cnki.issn1007-7693.2018.05.032 |
| 分类号:R952 |
| 基金项目: |
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| Screening and Analysis of Safety Failure Modes of Ganciclovir in Pediatric Drug Therapy |
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ZHAO Jie, ZHANG Guandong, XUE Zhimin, YANG Yu, GAO Yanfei, HAN Yan, ZHAO Ruiling
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Pharmacy Department, Children's Hosptial of Shanxi Provence, Taiyuan 030013, China
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| Abstract: |
| OBJECTIVE To analysis the risks of ganciclovir using in children, and to formulate security policy.METHODS The failure mode and effect analysis method were used to search for the failure modes of ganciclovir in pediatric drug therapy by literature searching, questionnaire survey, field investigation and other steps.RESULTS Five failure modes of ganciclovir in pediatric drug therapy were obtained through the risk priority score, and precautionary strategies were established for these failure modes.CONCLUSION There are still many risks of ganciclovir in all aspects of pediatric clinical use. In China, there are few laws on children's rational use of drugs. |
| Key words: ganciclovir children failure modes and effects analysis |
