| 引用本文: | 王丹丹,陈超,陈瑜,俞辉.DSC法鉴别高风险塑料输液产品[J].中国现代应用药学,2018,35(2):174-176. |
| WANG Dandan,CHEN Chao,CHEN Yu,YU Hui.Identification of Plastic Infusion Products of High Risk by DSC[J].Chin J Mod Appl Pharm(中国现代应用药学),2018,35(2):174-176. |
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| 摘要: |
| 目的 建立高风险塑料输液产品的差示扫描量热分析鉴别方法。方法 初始温度40 ℃，以20 ℃·min-1加热到200 ℃，再以20 ℃·min-1降温到40 ℃，然后以10 ℃·min-1加热到200 ℃，记录DSC图谱。结果 聚丙烯输液瓶、塑料输液容器用聚丙烯组合盖（拉环式，内盖）、三层共挤输液用膜（袋）和五层共挤输液用膜（袋）均显示其特征DSC图谱。结论 该方法准确、灵敏、简便，适用于对高风险塑料输液产品的鉴别。 |
| 关键词: 差示扫描量热法 塑料输液产品 聚丙烯输液瓶 塑料输液容器用聚丙烯组合盖(拉环式) 三层共挤输液用膜(袋) 五层共挤输液用膜(袋) |
| DOI：10.13748/j.cnki.issn1007-7693.2018.02.005 |
| 分类号:R917.1 |
| 基金项目: |
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| Identification of Plastic Infusion Products of High Risk by DSC |
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WANG Dandan1,2, CHEN Chao1, CHEN Yu1, YU Hui1
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1.Zhejiang Institute for Food and Drug Control, Key Laboratory of Drug Contacting Materials Quality Control of Zhejiang Province, Hangzhou 310052, China;2.Zhejiang University of Technology, Hangzhou 310004, China
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| Abstract: |
| OBJECTIVE To develop a method for identification of plastic infusion products of high risk by differential scanning calorimetry (DSC). METHODS The initial temperature was 40℃, then heated to 200℃ by 20℃·min-1, cooled to 40℃ by 20℃·min-1, then heated to 200℃ by 10℃·min-1, recorded the DSC spectrum.RESULTS PP infusion bottles, combinational closures of PP for plastic infusion containers (with ring-pull) (inner closure), 3-layer co-extrusion film (bag) for infusion, 5-layer co-extrusion film (bag) for infusion showed specific DSC spectrum, respectively. CONCLUSION This method is accurate, sensitive, simple, it can be used for identification of plastic infusion products of high risk. |
| Key words: differential scanning calorimetry (DSC) plastic infusion products PP infusion bottles combinational closures of PP for plastic infusion containers (with ring-pull) 3-layer co-extrusion film (bag) for infusion 5-layer co-extrusion film (bag) for infusion |
