| 引用本文: | 黄周锋,卢文杰,谭晓,陆国寿,黄建猷,胡筱希.裸花水竹草脂溶性成分及其抗氧化活性研究[J].中国现代应用药学,2018,35(5):674-677. |
| HUANG Zhoufeng,LU Wenjie,TAN Xiao,LU Guoshou,HUANG Jianyou,HU Xiaoxi.Study on the Components and Antioxidant Activites of the Liposoluble Constituents from Murdannia Nudiflora (Linn.) Brenan[J].Chin J Mod Appl Pharm(中国现代应用药学),2018,35(5):674-677. |
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| 摘要: |
| 目的 分析裸花水竹草的脂溶性成分及其抗氧化活性。方法 利用气相色谱-质谱（GC-MS）联用技术对裸花水竹草药材的脂溶性成分进行分析和鉴定，并通过标准质谱谱库的计算机检索进行化学成分定性；采用清除DPPH自由基及ABTS自由基能力的方法对裸花水竹草的脂溶性成分进行抗氧化活性研究。结果 从裸花水竹草的脂溶性成分中共鉴定出23个成分，同时抗氧化结果显示裸花水竹草的脂溶性成分对DPPH自由基及ABTS自由基的半数清除浓度IC50分别为5.255，3.848 mg·mL-1。结论 裸花水竹草的脂溶性成分主要为不饱和脂肪酸类化合物及植醇，均为首次从该植物中鉴定出；其脂溶性成分具有一定的抗氧化活性。 |
| 关键词: 裸花水竹草 脂溶性成分 气相色谱-质谱联用 抗氧化活性 |
| DOI：10.13748/j.cnki.issn1007-7693.2018.05.012 |
| 分类号:R285 |
| 基金项目:广西中药质量标准研究重点实验室系统性研究课题（桂中重系201309） |
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| Study on the Components and Antioxidant Activites of the Liposoluble Constituents from Murdannia Nudiflora (Linn.) Brenan |
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HUANG Zhoufeng1, LU Wenjie1,2, TAN Xiao1, LU Guoshou1, HUANG Jianyou1, HU Xiaoxi1
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1.Guangxi Institute of Chinese Medicine & Pharmaceutical Science, Nanning 530022, China;2.Guangxi Key Laboratory of Traditional Chinese Medicine Quality Stardands, Nanning 530022, China
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| Abstract: |
| OBJECTIVE To analyze the components and antioxidant activites of the liposoluble constituents from Murdannia nudiflora (Linn.) Brenan.METHODS The liposoluble constituents from Murdannia nudiflora (Linn.) Brenan were analyzed by GC-MS and identified by the searching of standard mass spectral library on computer. The antioxidant activites were detected by DPPH free radical and ABTS free radical scavenging method.RESULTS The 23 compounds were identified from Murdannia nudiflora (Linn.), and the half elimination ratio (IC50) of scavenging activity of free radical in DPPH and ABTS were 5.255, 3.848 mg·mL-1, respectively.CONCLUSION The bioassay indicated that the liposoluble constituents from Murdannia nudiflora (Linn.) Brenan possessed antioxidant activites. Unsaturated fatty acid and phytol are major chemical constituents of these components. All the compounds were identified from this plant for the first time. The liposoluble constituents from Murdannia nudiflora (Linn.) Brenan possessed antioxidant activites. |
| Key words: Murdannia nudiflora(Linn.) Brenan the liposoluble constituents GC-MS the antioxidant activites |
