| 引用本文: | 魏斌,刘兰茹,吴红英,龙伟.α-黑素细胞刺激素的药理作用研究进展[J].中国现代应用药学,2017,34(9):1351-1355. |
| WEI Bin,LIU Lanru,WU Hongying,LONG Wei.Advances in Pharmacological Effects of Alpha-melanocyte-stimulating Hormone[J].Chin J Mod Appl Pharm(中国现代应用药学),2017,34(9):1351-1355. |
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| 摘要: |
| α-黑素细胞刺激素（α-MSH）是来源于阿黑皮素原的一种神经内分泌免疫调节肽，在中枢神经和外周器官都有分布，具有广泛的生理活性，近年来对其开展了大量的研究，取得了良好的进展。本文综述了其抗炎、抗黑色素瘤、退热、保护皮肤、抑制肥胖、抗艾滋病等方面的药理作用研究进展，旨在为相关新药的研发提供参考。 |
| 关键词: α-黑素细胞刺激素 黑色素瘤 抗炎 神经系统 |
| DOI：10.13748/j.cnki.issn1007-7693.2017.09.031 |
| 分类号:R961 |
| 基金项目:国家自然科学基金（81673106） |
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| Advances in Pharmacological Effects of Alpha-melanocyte-stimulating Hormone |
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WEI Bin, LIU Lanru, WU Hongying, LONG Wei
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Institute of Radiation Medicine, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin 300192, China
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| Abstract: |
| Alpha-melanocyte-stimulating hormone (α-MSH) is a neuroendocrine immunoregulatory peptide derived from pro-opiomelanocortin, which is distributed in the central nervous system and peripheral organs and has a wide range of physiological activities and has been developed in recent years. A lot of research has made good progress. This paper reviews the progress of its pharmacological effects in anti-inflammatory, anti-melanoma, fever, skin protection, obesity and anti-AIDS, and aims to provide reference for the development of new drugs. |
| Key words: alpha-melanocyte-stimulating hormone melanoma anti-inflammatory nervous system |
