| 引用本文: | 郭晓静,陆家瑜,陆萌萌,邵正威,邹德荣.抗骨质疏松药物雷奈酸锶的研究进展[J].中国现代应用药学,2017,34(6):907-912. |
| GUO Xiaojing,LU Jiayu,LU Mengmeng,SHAO Zhengwei,ZOU Derong.Research Progress of Strontium Ranelate, an Anti-osteoporosis Drug[J].Chin J Mod Appl Pharm(中国现代应用药学),2017,34(6):907-912. |
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| 摘要: |
| 雷奈酸锶是目前临床应用的一种兼具促进成骨和抑制破骨吸收双重作用的抗骨质疏松药物，具有优秀的抗骨质疏松效果。本文综述了雷奈酸锶基础和临床研究的研究进展，并讨论了近年来该药出现的不良反应和新的应用前景，为今后进一步研究和临床用药选择提供依据。 |
| 关键词: 雷奈酸锶 骨质疏松 研究进展 不良反应 应用前景 |
| DOI：10.13748/j.cnki.issn1007-7693.2017.06.028 |
| 分类号: |
| 基金项目:国家自然科学基金资助项目（31400825，81470714）；上海市科学技术委员会（15410722600）；上海市第六人民医院预研基金（LYZY-0082）；上海交通大学医学院博士创新基金；上海交通大学医学院转化医学创新基金（15ZH2012） |
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| Research Progress of Strontium Ranelate, an Anti-osteoporosis Drug |
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GUO Xiaojing, LU Jiayu, LU Mengmeng, SHAO Zhengwei, ZOU Derong
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Department of Stomatology, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai 200233, China
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| Abstract: |
| Strontium ranalate is an anti-osteoporosis drug with both promoting bone formation and inhibiting bone resorption effects, can provide outstanding clinical benefits for the patients. The paper systematically reviewed the basic and cilincial studies of strontium ranalate. The adverse reaction as well as new applications of strontium ranelate have also been discussed to lay the foundation for further experimental and clinical study. |
| Key words: strontium ranelate osteoporosis research progress adverse reaction further application |
