| 引用本文: | 任红,姚建标,金辉辉,王如伟.不同年份、不同产地西红花药材的质量研究[J].中国现代应用药学,2016,33(11):1405-1408. |
| REN Hong,YAO Jianbiao,JIN Huihui,WANG Ruwei.Quality Study on Croci Stigma Collected in Different Years and Different Place[J].Chin J Mod Appl Pharm(中国现代应用药学),2016,33(11):1405-1408. |
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| 不同年份、不同产地西红花药材的质量研究 |
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任红1,2, 姚建标3, 金辉辉3, 王如伟1,3
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1.浙江中医药大学药学院, 杭州 310053;2.浙江现代中药与天然药物研究院有限公司, 杭州 310051;3.浙江康恩贝制药股份有限公司, 杭州 310051
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| 摘要: |
| 目的 通过对不同年份、不同产地的西红花药材进行质量分析，评价储藏年份以及产地对药材质量的影响。方法 收集不同年份、不同产地的西红花药材，对其进行质量考察，主要包括药材鉴定和含量测定。结果 随着储存年份的延长，西红花药材有不同程度的褪色情况，且西红花总苷含量呈降低趋势；比较不同产地的西红花药材，结果发现，建德、上海产的西红花药材西红花总苷含量>10％，国外的西红花药材部分批次没有达到药典要求。结论 随着保存年份的增加，西红花药材的外观性状以及西红花苷含量会有较大改变，采取特殊的保存措施能抑制其含量的降低；且不同产地的西红花药材中西红花苷含量也不同，国产药材西红花苷含量较高，可能与加工和保存方法有关。 |
| 关键词: 不同年份 不同产地 西红花总苷 |
| DOI：10.13748/j.cnki.issn1007-7693.2016.11.012 |
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| 基金项目:浙江省大学生科技创新活动计划 暨新苗人才计划项目 |
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| Quality Study on Croci Stigma Collected in Different Years and Different Place |
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REN Hong1,2, YAO Jianbiao3, JIN Huihui3, WANG Ruwei1,3
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1.Pharmacy College of Zhejiang Chinese Medicine University, Hangzhou 310053, China;2.Zhejiang Modern Traditional Chinese Medicine and Natural Medicine Research Institute Co., Ltd., Hangzhou 310051, China;3.Zhejiang CONBA Pharmaceutical Co., Ltd., Hangzhou 310051, China
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| Abstract: |
| OBJECTIVE To evaluate the influence of the storage year and places of origin on the quality of medicinal materials through the quality analysis for the Croci Stigma of different years and different places. METHODS The Croci Stigma of different years and different places were collected to study the quality inspection, mainly including the identification and content determination of medicinal herbs. RESULTS As the extension of storage year, the Croci Stigma had faded in different degrees, and the total glycosides content of Croci Stigma showed a trend of decrease; Compared the Croci Stigma of different regions, the results showed that the total glycosides content of Croci Stigma made in Shanghai and Jiande were >10%, some batches of Croci Stigma abroad didn't reach the requirements of pharmacopoeia. CONCLUSION As the extension of storage year, the appearance of the Croci Stigma and the content of total glycosides in Croci Stigma will be a big change, while taking some special preservation measures can inhibit the decrease of its content; and the Croci Stigma glycosides content in different places are also different, domestic medicinal materials have higher glycosidescontent of Croci Stigma, which may be related to the processing and preservation methods. |
| Key words: different years different places crocins |
