| 引用本文: | 谢华,袁海玲,陈玉芳,李连海,唐玲芳,杨霞,张文.含辅料注射剂的临床合理用药[J].中国现代应用药学,2016,33(4):488-492. |
| XIE Hua,YUAN Hailing,CHEN Yufang,LI Lianhai,TANG Lingfang,YANG Xia,ZHANG Wen.Clinical Rational Drug Use for Pharmaceutical Excipients of Injection[J].Chin J Mod Appl Pharm(中国现代应用药学),2016,33(4):488-492. |
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| 摘要: |
| 目的 掌握含辅料注射剂药品说明书中辅料的标明情况，为临床合理用药提供依据。方法 查阅本院注射剂药品说明书，对药品中所含辅料的标明情况进行统计分析。结果 注射用药品共278种，64.75%标明了所含辅料成分；标明辅料品种的共有61种，55.74%被中国药典2015年版所收载；标明辅料的注射剂药品说明书中，分别有2.78%，21.11%，3.89%及0.56%的药品标示了与辅料相关不良反应、禁忌症、注意事项及药物相互作用。结论 临床用药时不仅要关注药品的疗效和不良反应，还要考虑药用辅料的不良反应及其与药物之间的相互作用，以确保临床合理用药。 |
| 关键词: 药用辅料 注射剂 合理用药 |
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| Clinical Rational Drug Use for Pharmaceutical Excipients of Injection |
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XIE Hua, YUAN Hailing, CHEN Yufang, LI Lianhai, TANG Lingfang, YANG Xia, ZHANG Wen
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Department of Pharmacy, Anning Branch Lanzhou General Hospital Lanzhou Command, Lanzhou 730070, China
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| Abstract: |
| OBJECTIVE To grasp the drug prospectus for pharmaceutical excipients of injection, and provide basis for rational use of drugs. METHODS To count and analyze the information for pharmaceutical excipients of injection by review the prospectus of injection in our hospital. RESULTS There were 64.75% prospectus of 278 injections marked with pharmaceutical excipients. There were 61 kinds of pharmaceutical excipients which 55.74% were recorded in 2015 Chinese Pharmacopoeia. There were 2.78%, 21.11%, 3.89% and 0.56% drug prospectus for pharmaceutical excipients of injection warninged related adverse reactions, contraindications, precautions and drug interaction. CONCLUSION In order to ensure the clinical rational use of drugs, physicians and clinical pharmacists should not only pay attention to the efficacy and adverse reactions of drugs, but also to consider the adverse reactions of pharmaceutical excipients and the interactions between drugs and pharmaceutical excipients. |
| Key words: pharmaceutical excipients injection rational use of drugs |
