| 引用本文: | 柳茜,郑丹俊,莫建霞,甘礼社,周长新.黄三七化学成分的研究[J].中国现代应用药学,2015,32(10):1165-1169. |
| LIU Qian,ZHENG Danjun,MO Jianxia,GAN Lishe,ZHOU Changxin.Study on the Chemical Constituents from Souliea Vaginata (Maxim.) Franch[J].Chin J Mod Appl Pharm(中国现代应用药学),2015,32(10):1165-1169. |
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| 摘要: |
| 目的 研究黄三七的化学成分。方法 采用多种色谱方法对黄三七全草的乙醇提取物进行分离纯化，并应用现代波谱技术对得到的化合物进行结构鉴定。结果 共分离得到6个环菠萝蜜烷型三萜类化合物，分别鉴定为cimilactoneA(1)、23-Epi-26-deoxyactein(2)、soulieosides I(3)、neocimicigenoside B(4)、asiaticoside A(5)、25-O-acetylcimigenol-3-O-β-D- xylopyranoside(6)。结论 环菠萝蜜烷型三萜类化合物是黄三七的特征性成分，化合物1、4和5为首次从该属植物中分离得到。 |
| 关键词: 黄三七 化学成分 环菠萝蜜烷型三萜 |
| DOI： |
| 分类号:R284.1 |
| 基金项目:国家自然科学基金(21372198) |
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| Study on the Chemical Constituents from Souliea Vaginata (Maxim.) Franch |
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LIU Qian, ZHENG Danjun, MO Jianxia, GAN Lishe, ZHOU Changxin
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Institute of Modern Chinese Medicine, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China
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| Abstract: |
| OBJECTIVE To study the chemical constituents of the ethanol extract from the plant Souliea vaginata (Maxim.) Franch. METHODS The chemical constituents were isolated by multi-chromatographic methods as silica gel, macroporous resin, MCI, Sephadex LH-20, C18-reversed-phase chromatography. The structures were identified on the basis of chemical methods and spectroscopic evidence. RESULTS Six cycloartane triterpenoid compounds were isolated and identified as cimilactone A (1), 23-Epi-26-deoxyactein (2), soulieosides I (3), neocimicigenoside B (4), asiaticoside A (5), 25-O- acetylcimigenol-3-O-β-D-xylopyranoside (6). CONCLUSION Cycloartane triterpenoids existed as characteristic constituents in Souliea vaginata (Maxim.) Franch. Compound 1, 4 and 5 were separated from this species for the first time. |
| Key words: Souliea vaginata (Maxim.) Franch chemical constituents cycloartane triterpenoids |
