| 引用本文: | 王宇,徐颖颖,张相彩,郑韧,朱圣婷,王怀冲.钙离子拮抗剂类降压药的临床应用及不良反应[J].中国现代应用药学,2015,32(3):385-390. |
| WANG Yu,XU Yingying,ZHANG Xiangcai,ZHENG Ren,ZHU Shenting,WANG Huaichong.Calcium Channel Blockers of Clinical Application and Adverse Reactions[J].Chin J Mod Appl Pharm(中国现代应用药学),2015,32(3):385-390. |
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| 摘要: |
| 目的 对钙离子拮抗剂在临床中的临床应用及不良反应做系统的分析，总结钙离子拮抗剂在临床中的应用及注意事项，为药师在临床用药监测中提供了理论支持。方法 通过查阅文献的方式，系统学习钙离子拮抗剂的临床应用及不良反应。结果 钙离子拮抗剂广泛应用于心血管等多种疾病，其不良反应有心律失常、低血压、房室传导阻滞、心力衰竭、牙龈增生、外周水肿、便秘等。药物使用应关注其常见和罕见的不良反应，促进合理用药。结论 药物在使用过程中，不仅要注重药物的药理作用及临床疗效，最好在使用之前就预见药物的不良反应，才能做到及时防治，最大地发挥药物疗效。 |
| 关键词: 钙离子拮抗剂 降压 临床应用 不良反应 心血管系统 |
| DOI： |
| 分类号:R969.3 |
| 基金项目: |
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| Calcium Channel Blockers of Clinical Application and Adverse Reactions |
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WANG Yu, XU Yingying, ZHANG Xiangcai, ZHENG Ren, ZHU Shenting, WANG Huaichong
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Department of Pharmacy, Hangzhou Red Cross Hospital, Hangzhou 310006, China
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| Abstract: |
| OBJECTIVE To understand the calcium channel blockers in clinical application and precautions for pharmacists to provide a theoretical support for clinical drug monitoring by reviewing calcium channel blockers in clinical application and adverse reactions of the system. METHODS The literature of the way, the systematic study of clinical applications and adverse reactions calcium channel blockers were reviewed. RESULTS Calcium channel blockers were widely used in cardiovascular and other diseases, adverse reactions included arrhythmia, hypotension, atrioventricular block, heart failure, gingival hyperplasia, peripheral edema, constipation. Its common and rare adverse reactions should be focused to promote rational drug use. CONCLUSION The use of a class of drugs in the process, not only to focus on the pharmacological effects of drugs and clinical efficacy, better before using foresaw adverse drug reactions, in order to achieve prevention and treatment, the efficacy of the biggest play of the drug. |
| Key words: calcium channel blockers hypotensive clinical application adverse reactions cardiovascular system |
