| 引用本文: | 吴健,李颖,李翔,高家荣,罗欢.干预前后氨曲南的临床应用及安全性评价[J].中国现代应用药学,2014,31(10):1259-1263. |
| WU Jian,LI Ying,LI Xiang,GAO Jiarong,LUO Huan.Clinical Application and Safty Assessment of Aztreonam Before and After Intervention[J].Chin J Mod Appl Pharm(中国现代应用药学),2014,31(10):1259-1263. |
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| 摘要: |
| 目的 通过分析干预前后氨曲南的使用情况，为临床合理用药提供依据。方法 采用回顾性调查方法，对2012年和2013年第2季度笔者所在医院氨曲南的使用情况和不良反应进行分析。结果 干预前有无适应证选药、用法用量错误及联合用药不合理等现象，干预后氨曲南使用基本合理，不良反应发生率为0.67%。结论 氨曲南临床应用干预效果明显，干预后氨曲南应用不合理情况明显降低。 |
| 关键词: 氨曲南 抗菌药物 临床应用 安全性评价 干预 |
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| 基金项目:国家中医药重点学科(临床中药学)建设项目(国中医药人教发〔2012〕32号)；国家中医药管理局“十二五”重点专科(临床药学)培育项目(国中医药医政发〔2012〕2号) |
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| Clinical Application and Safty Assessment of Aztreonam Before and After Intervention |
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WU Jian, LI Ying, LI Xiang, GAO Jiarong, LUO Huan
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The First Affiliated Hospital of Anhui University of Chinese Medicine, Hefei 230031, China
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| Abstract: |
| OBJECTIVE To analysis the utilization in patients in order to promote rational use of antimicrobial agents before and after intervention. METHODS By retrospective study, the use and ADR of aztreonam in outher’s hospital during April to June period of 2012 and 2013 were analyzed. RESULTS Before intervention, in some cases, the use of aztreonam was irrational in drug choice, dosage, administration and drug combination, etc. After intervention, the use of aztreonam in outher’s hospital was rational, the incidence of ADR was 0.67%. CONCLUSION The intervention on clinical use of aztreonam achieved remarkable outcome, unreasonable use of aztreonam reduced significantly after intervention. |
| Key words: aztreonam antibacterial agents clinical application safety evaluation intervention |
