| 引用本文: | 常青鲜,王宗权,贾继明.益智仁水提物的化学成分研究(Ⅰ)[J].中国现代应用药学,2014,31(5):549-551. |
| CHANG Qingxian,WANG Zongquan,JIA Jiming.Chemical Constituents from the Water Extract of Alpinia Oxyphylla Miq. (Ⅰ)[J].Chin J Mod Appl Pharm(中国现代应用药学),2014,31(5):549-551. |
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| 摘要: |
| 目的 研究益智仁(Alpinia oxyphylla Miq.)水提物中的化学成分。方法 采用溶剂法、Sephadex LH-20柱色谱法等对益智仁的化学成分进行分离纯化，运用波谱技术鉴定其结构。结果 从益智仁水提物中分离得到了5个化合物，分别鉴定为原儿茶醛(1)、原儿茶酸(2)、对香豆酸(3)、(-)-表儿茶素(4)、(+)-儿茶素(5)。结论 化合物1，3和4为首次从该属植物中分离得到，化合物5为首次从该植物中分离得到。 |
| 关键词: 益智仁 水提物 化学成分 分离鉴定 |
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| 基金项目:] “重大新药创制”科技重大专项(2011ZX09401-020)；国家重点基础研究发展计划项目(2012CB518606)；国家青年科学基金(81102768) |
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| Chemical Constituents from the Water Extract of Alpinia Oxyphylla Miq. (Ⅰ) |
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CHANG Qingxian, WANG Zongquan, JIA Jiming
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Shijiazhuang Yiling Pharmaceutical Co., Ltd, Shijiazhuang 050035, China
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| Abstract: |
| OBJECTIVE To study the chemical constituents from the water extract of Alpinia oxyphylla Miq.. METHODS The chemical constituents were isolated by solvent and Sephadex LH-20 methods. The structures were identified on the basis of chemical methods and spectroscopic evidence. RESULTS Five compounds were identified as protocatechuic aldehyde(1), protocatechuic acid(2), p-coumaric acid(3), (-)-epicatechin(4), (+)-catechin(5). CONCLUSION Compounds 1, 3 and 4 are obtained for the first time from this genus and compound 5 is obtained for the first time from this species. |
| Key words: Alpinia oxyphylla Miq. water extracts chemical constituent isolation and identification |
