| 引用本文: | 朱兰寸,刘志华,李高,宋思才,马廷升.超临界CO2流体萃取分离广东紫珠总黄酮的研究[J].中国现代应用药学,2014,31(6):702-706. |
| ZHU Lancun,LIU Zhihua,LI Gao,SONG Sicai,MA Tingsheng.Supercritical Fluid CO2 Extraction Technology of Flavonoids from Callicarpa Kwangtungensis Chun.[J].Chin J Mod Appl Pharm(中国现代应用药学),2014,31(6):702-706. |
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| 摘要: |
| 目的 研究超临界CO2流体提取广东紫珠中总黄酮的最佳工艺。方法 采用正交试验，考察提取压力、温度、时间以及夹带剂用量对广东紫珠中总黄酮化合物提取率的影响。结果 超临界CO2流体提取广东紫珠总黄酮化合物最佳工艺条件为：压力40 MPa、温度40 ℃、时间1 h、夹带剂用量为4.5 mL·g-1，最佳条件下总黄酮提取率为6.27%，含量为65.21%。结论 超临界CO2流体提取广东紫珠总黄酮工艺简单、提取率高。 |
| 关键词: 广东紫珠 超临界CO2流体 黄酮类化合物 |
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| 基金项目:湖南省教育厅自然科学基金资助项目(11C1012) |
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| Supercritical Fluid CO2 Extraction Technology of Flavonoids from Callicarpa Kwangtungensis Chun. |
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ZHU Lancun1, LIU Zhihua1, LI Gao2, SONG Sicai3, MA Tingsheng1
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1.Pharmacology Department of Hunan University of Medicine, Huaihua 418000, China;2.Tongji Medical College of Huazhong University of Science and Technology, Wuhan 430030, China;3.Technological Department of Zhenghao Pharmaceutical Factory in Huaihua, Huaihua 418000, China
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| Abstract: |
| OBJECTIVE To study the technology of supercritical fluid CO2 extraction (SFE CO2) on flavonoids from Callicarpa kwangtungensis Chun. METHODS The effects of pressure, temperature, time and volume of entrainer on flavonoids extracts were studied by orthogonal test. The optimum condition for SFE CO2 was determined. RESULTS The optimum extraction conditions were as follows: pressure 40.0 MPa, temperature 40 ℃, time 1.0 h and absolute ethyl alcohol entrainer, content 4.5 mL·g-1 materials. The yield of flavonoids was 6.27%, and the content was 65.21%. CONCLUSION The optimum extraction has high extraction ratio of flavonoids. The optimum extraction is reasonable and practicable1. |
| Key words: Callicarpa kwangtungensis Chun supercritical CO2 extraction flavonoids |
