| 引用本文: | 陆静娴,罗镭,陈勇,陈建,祝明.乌灵菌粉化学成分研究[J].中国现代应用药学,2014,31(5):541-543. |
| LU Jingxian,LUO Lei,CHEN Yong,CHEN Jian,ZHU Ming.Chemical Constituents of Wuling Fermentative Powder[J].Chin J Mod Appl Pharm(中国现代应用药学),2014,31(5):541-543. |
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| 摘要: |
| 目的 对乌灵菌粉的化学成分进行研究。方法 采用硅胶柱层析、制备液相等多种分离手段，对乌灵菌粉中石油醚、乙酸乙酯部分进行提取、分离、纯化，通过核磁数据进行结构鉴定。结果 分离并鉴定4个化合物，分别为: 5-hydroxymellein(1)、5-carboxylmellein(2)、金雀异黄素(3)和5-methylmellein(4)。结论 化合物2，3，4为首次从乌灵菌粉提取分离得到；化合物1，2，4为乌灵菌粉的特征性成分。 |
| 关键词: 乌灵菌粉 化学成分 |
| DOI： |
| 分类号:R284.1 |
| 基金项目:“重大新药创制”国家科技重大专项(2012ZX09304005) |
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| Chemical Constituents of Wuling Fermentative Powder |
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LU Jingxian1, LUO Lei1, CHEN Yong1, CHEN Jian2, ZHU Ming1
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1.Zhejiang Institute for Food and Drug Control, Hangzhou 310004, China;2.Zhejiang Jolly Pharmaceutical Co. Ltd., Huzhou 313299, China
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| Abstract: |
| OBJECTIVE To study the chemical constituents of Wuling fermentative powder. METHODS Four components were extracted, separated and purified from the parts of petroleum and acetic ether by the means of silica gel column chromatography and preparative HPLC methods, and identified by NMR data. RESULTS The four compounds were elucidated as: 5-hydroxymellein(1), 5-carboxylmellein(2), genistein(3) and 5-methylmellein(4). CONCLUSION The later three components are obtained for the first time from Wuling Fermentative powder. 1, 2 and 4 are the characteristic components in Wuling Fermentative powder. |
| Key words: Wuling fermentative powder chemical constituents |
