| 引用本文: | 杨毅,孙乙铭,徐建中,俞旭平.延胡索加工炮制一体化饮片与传统炮制饮片镇痛作用比较[J].中国现代应用药学,2013,30(10):1074-1077. |
| YANG Yi,SUN Yiming,XU Jianzhong,YU Xuping.Comparison of Analgesic Effect of Corydalis Yanhusuo Decoction Pieces by Processing Integration and Traditional Processing[J].Chin J Mod Appl Pharm(中国现代应用药学),2013,30(10):1074-1077. |
|
| 摘要: |
| 目的 比较加工炮制一体化延胡索饮片与传统工艺炮制延胡索饮片的镇痛作用。方法 采用热板法、小鼠扭体法、热水缩尾法观察新炮制工艺延胡索与传统炮制延胡索的镇痛作用。结果 加工炮制一体化延胡索饮片与传统加工炮制延胡索饮片均能提高小鼠热板法的痛阈值，与生理盐水组比较差异有统计学意义(P<0.05)；加工炮制一体化延胡索镇痛作用优于传统加工炮制延胡索，差异有统计学意义(P<0.05)。结论 加工炮制一体化延胡索饮片的镇痛作用优于传统加工炮制延胡索。 |
| 关键词: 延胡索 加工炮制一体化 传统炮制 镇痛 |
| DOI： |
| 分类号: |
| 基金项目:浙江省科技计划项目(2008C13035-1；2011C22055)；2010、2012年浙江省经信委中药现代化项目；浙江省“十二五”中药材新品种选育项目(2012C12912) |
|
| Comparison of Analgesic Effect of Corydalis Yanhusuo Decoction Pieces by Processing Integration and Traditional Processing |
|
YANG Yi, SUN Yiming, XU Jianzhong, YU Xuping
|
|
Zhengjiang Research Institute of Traditional Chinese Medicine, Hangzhou 310023, China
|
| Abstract: |
| OBJECTIVE To compare analgesic effect of Corydalis yanhusuo decoction pieces by two processing technology: processing integration and traditional processing. METHODS By applying the hot plate, writhing body and tail-immersion test methods in mice, experiments were performed to observe analgesic effect of Corydalis yanhusuo decoction pieces by the two different processing technology. RESULTS The mice's pain threshold caused by hot board was improved by Corydalis yanhusuo decoction pieces both by the two processing technology, there were significant differences compared with normal saline groups(P<0.05). The analgesia effect of Corydalis yanhusuo decoction pieces by processing integration was superior to the traditional processing, the difference was statistically significant(P<0.05). CONCLUSION Corydalis yanhusuo decoction pieces by processing integration has analgesic effect which is superior to that by traditional processing. |
| Key words: Corydalis yanhusuo processing integration traditional processing analgesia |
