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引用本文:郭志渊,傅萍,谢华,张悦杨.茴拉西坦有关物质测定方法的改进[J].中国现代应用药学,2013,30(1):84-86.
GUO Zhiyuan,FU Ping,XIE Hua,ZHANG Yueyang.Improved HPLC Method for Determination of Related Substances in Aniracetam[J].Chin J Mod Appl Pharm(中国现代应用药学),2013,30(1):84-86.
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茴拉西坦有关物质测定方法的改进
郭志渊, 傅萍, 谢华, 张悦杨
四川省食品药品检验所,成都 610097
摘要:
目的 改进茴拉西坦的有关物质测定方法。方法 采用高效液相色谱法,以C18为色谱柱,流动相为乙腈-水(35∶65),检测波长为254 nm。结果 茴拉西坦与其降解产物在该色谱条件下能够有效分离。结论 该方法准确可靠,可用于测定茴拉西坦的有关物质测定。
关键词:  高效液相色谱法  茴拉西坦  有关物质
DOI:
分类号:
基金项目:
Improved HPLC Method for Determination of Related Substances in Aniracetam
GUO Zhiyuan, FU Ping, XIE Hua, ZHANG Yueyang
Sichuan Institute for Food and Drug Control, Chengdu 610097, China
Abstract:
OBJECTIVE To improve an HPLC method for determination of the related substances in aniracetam. METHODS The column was C18 colum. Mobile phase was acetonitrile-water(35∶65). The detection wavelength was 254 nm. RESULTS Aniracetam and its related substances can be separated effectively by this method. CONCLUSION The method is accurate and reliable. It can be used for the related substances determination in aniracetam.
Key words:  HPLC  aniracetam  related substances
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