| 引用本文: | 尹永芹,张鑫,黄峰,沈志滨,崔红花,陶曙红.了哥王的化学成分研究[J].中国现代应用药学,2012,29(8):697-699. |
| YIN Yongqin,ZHANG Xin,HUANG Feng,SHEN Zhibin,CUI Honghua,TAO Shuhong.Chemical Constituents of Wikstroemia Indica[J].Chin J Mod Appl Pharm(中国现代应用药学),2012,29(8):697-699. |
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| 摘要: |
| 目的 研究了哥王Wikstroemia indica (L.) C. A. Mey.化学成分。方法 运用硅胶、凝胶等多种色谱技术对了哥王的化学成分进行研究，并根据理化性质和波谱数据鉴定化合物结构。结果 从了哥王85%乙醇提取物的醋酸乙酯和正丁醇萃取部位分离并鉴定了9个化合物，分别为西瑞香素(daphnoretin)、柚皮素(naringin)、3,5,7-二羟基-4'-甲氧基二氢黄酮醇(3,5,7-trihydroxy-4′-methoxy-dihydroflavonol)、对羟基苯甲酸(4-hydroxybenzoic acid)、苯甲酸(benzoic-acid)、伞形花内酯(umbdheforne)、daphnogitin、sikokianin B、芫花素(genkwanin)。结论 化合物2~5为首次从该植物中分离得到。 |
| 关键词: 荛花属 了哥王 西瑞香素 柚皮素 化学成分 |
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| 基金项目:科技部“十二五”“重大新药创制”项目(2011ZX09102-007-03)；广东省科技厅科技计划重点专项(2011A030100013)；广东省科技厅科技计划项目(2010B030700044)；2010年广东省教育厅高层次人才资助项目 |
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| Chemical Constituents of Wikstroemia Indica |
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YIN Yongqin, ZHANG Xin, HUANG Feng, SHEN Zhibin, CUI Honghua, TAO Shuhong
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School of Traditional Chinese Medicinal Chemistry, Guangdong Pharmaceutical University, Guangzhou 510006, China
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| Abstract: |
| OBJECTIVE To study the chemical constitutents from Wikstroemia indica (L.) C. A. Mey. METHODS Silica gel column, Sephadex LH-20 column chromatography were used for separation and purification of the compounds and extensive spectral analysis spectrum were employed for structural elucidation. RESULTS Nine compounds were isolated from EtOAc and n-butanol fraction of the 85% ethanol extract of the W. indica and identified as daphnoretin, naringin, 3,5,7-trihydroxy-4′-methoxy-dihydroflavonol, 4-hydroxybenzoic acid, benzoic-acid, umbdheforne, daphnogitin, sikokianin B, and genkwanin. CONCLUSION Compounds 2-5 are obtained from the plants of W. indica for the first time. |
| Key words: Wikstroemia Wikstroemia indica daphnoretin naringin chemical constituents |
