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引用本文:雷虹,华俊彦,田伟强,张丽芬.头孢噻利与甲硝唑注射液的配伍稳定性考察[J].中国现代应用药学,2012,29(3):274-276.
丽水市中心医院药剂科,浙江 丽水 323000.Compatible Stability of Cefoselis Sulsate with Metronidazole Injection[J].Chin J Mod Appl Pharm(中国现代应用药学),2012,29(3):274-276.
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头孢噻利与甲硝唑注射液的配伍稳定性考察
雷虹,华俊彦,田伟强,张丽芬
LEI Hong, HUA Junyan, TIAN Weiqiang*, ZHANG Lifen
摘要:
目的 考察头孢噻利与甲硝唑氯化钠注射液的配伍稳定性。方法 采用高效液相色谱法(HPLC)测定头孢噻利与甲硝唑氯化钠注射液配伍8 h内的含量变化,并考察其外观、pH 值变化。结果 头孢噻利与甲硝唑氯化钠注射液配伍后,8 h内二者含量变化不大,溶液澄清,pH值基本稳定。结论 头孢噻利与甲硝唑氯化钠注射液可配伍使用。
关键词:  头孢噻利  甲硝唑注射液  配伍稳定性
DOI:
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基金项目:浙江省医学会基金项目(2007ZYC57)
Compatible Stability of Cefoselis Sulsate with Metronidazole Injection
丽水市中心医院药剂科,浙江 丽水 323000
Department of Pharmacy, Lishui Central Hospital, Lishui 323000, China
Abstract:
OBJECTIVE To study the compatible stability of cefoselis sulsate with metronidazole injection. METHODS The content of the mixture of cefoselis sulsate and metronidazole within 8 h were determined by HPLC, meanwhile the changes in appearances and the pH values were observed. RESULTS The content of cefoselis sulsate and metronidazole injection was stable within 8 h. The mixture was clear, pH value was also stable. CONCLUSION Cefoselis sulsate can be mixed with metronidazole injection for clinical use.
Key words:  cefoselis sulsate  metronidazole injection  compatible stability
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