| 引用本文: | 雷成康,高琳,司马磊,黄萍,单敏.不同前处理过程的紫苏子配方颗粒生产工艺比较[J].中国现代应用药学,2022,39(18):2334-2338. |
| LEI Chengkang,GAO Lin,SI Malei,HUANG Ping,SHAN Min.Comparison of Process Technology for Perillae Fructus Formula Granules with Different Pretreatment Processes[J].Chin J Mod Appl Pharm(中国现代应用药学),2022,39(18):2334-2338. |
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| 摘要: |
| 目的 研究紫苏子不同前处理过程对配方颗粒生产工艺的影响。方法 以有效成分含量、特征图谱、出膏率、工艺的可行性以及成品质量等为指标评价不同前处理过程对配方颗粒的影响。结果 紫苏子经粉碎后的提取物其油脂含量较高，无法满足配方颗粒制剂要求，而未经处理直接提取虽然指标成分含量有所下降，但完全满足相关要求，可成功制得符合要求的配方颗粒。结论 在研制配方颗粒时，对果实种子类药材应视具体情况决定是否粉碎，不能一概而论。 |
| 关键词: 中药饮片 配方颗粒 紫苏子 工艺研究 |
| DOI：10.13748/j.cnki.issn1007-7693.2022.18.006 |
| 分类号:R283.1 |
| 基金项目:陕西省创新能力支撑计划项目(2018PT-29) |
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| Comparison of Process Technology for Perillae Fructus Formula Granules with Different Pretreatment Processes |
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LEI Chengkang, GAO Lin, SI Malei, HUANG Ping, SHAN Min
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Xi'an Institute for Food and Drug Control, Xi'an 710054, China
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| Abstract: |
| OBJECTIVE To study the effect of different pretreatment process on production process of Perillae Fructus formula granules.METHODS The content of active ingredients,fingerprint,extraction rate,feasibility of the process and quality of finished products were taken as indicators to evaluate the effect of different pretreatment process on formula granules.RESULTS The extract of Perillae Fructs after grinding had a lot of fat oil,which could not meet the requirements of formula granule preparation.Although the content of index components in the extract without grinding decreased,but it fully met the relevant requirements,and the formula granules could be successfully prepared.CONCLUSION In the development of formula granules,the fruit seed medicinal materials to be comminution or not should according to the specific conditions,which can not be generalized. |
| Key words: Chinese herbal pieces formula granules Perilla Fructus technology research |
