| 引用本文: | 李淑荣,王丽娜.温经通胞饮联合宫腹腔镜对输卵管阻塞性不孕症患者的疗效研究[J].中国现代应用药学,2021,38(4):463-467. |
| LI Shurong,WANG Lina.Study on Therapeutic Effect of Wenjing Tongbaoyin Combined with Hysteroscopy on Patients with Oviduct Obstructive Infertility[J].Chin J Mod Appl Pharm(中国现代应用药学),2021,38(4):463-467. |
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| 摘要: |
| 目的 探讨温经通胞饮联合宫腹腔镜对输卵管阻塞性不孕症患者的疗效。方法 选取2017年5月—2019年5月66例在河南中医药大学第一附属医院妇科住院治疗的通过宫腹腔镜联合手术获得输卵管复通的输卵管阻塞性不孕症（寒凝血瘀型）患者作为研究对象，采用简单随机法分组，将其分为2组，对照组予以常规治疗，观察组予以常规治疗+温经通胞饮治疗。比较2组患者治疗效果、输卵管通畅情况、妊娠情况、不良反应发生情况以及治疗前后炎性指标和血流变指标。结果 2组患者治疗有效率分别为66.67%，93.94%，观察组患者治疗有效率高于对照组（P<0.05）。2组患者治疗后输卵管通畅比较具有统计学差异（P<0.05），观察组患者输卵管通畅率高于对照组。观察组患者宫内妊娠率高于对照组，未孕率低于对照组（P<0.05）；2组患者异位妊娠率比较无统计学差异。2组患者治疗后白细胞介素6（interleukin，IL-6）、肿瘤坏死因子a （tumor necrosis factor-a，TNF-a）、血浆黏度、高切全血黏度、低切全血黏度水平均低于治疗前（P<0.05）；观察组患者治疗后IL-6、TNF-α、血浆黏度、高切全血黏度、低切全血黏度水平均低于对照组（P<0.05）。2组患者治疗期间均无不良反应情况发生。结论 温经通胞饮联合宫腹腔镜应用于输卵管阻塞性不孕症，可提高治疗效果，提高妊娠率，改善机体炎性状态及血流变。 |
| 关键词: 输卵管阻塞性不孕症 温经通胞饮 治疗效果 |
| DOI：10.13748/j.cnki.issn1007-7693.2021.04.014 |
| 分类号:R969.4 |
| 基金项目:河南省中医药科学研究专项课题（2018ZY2070）；河南省高等学校重点科研项目（19A360025） |
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| Study on Therapeutic Effect of Wenjing Tongbaoyin Combined with Hysteroscopy on Patients with Oviduct Obstructive Infertility |
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LI Shurong, WANG Lina
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Department of Obstetrics and Gynecology, The First Affiliated Hospital of Henan University of CM, Zhengzhou 450000, China
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| Abstract: |
| OBJECTIVE To explore the effect of Wenjing Tongbaoyin combined with hysteroscopy on patients with oviduct obstructive infertility. METHODS From May 2017 to May 2019, 66 cases of infertile tubal obstructive infertility(cold blood stasis type) patients who were hospitalized in the gynecology department of The First Affiliated Hospital of Henan University of CM and received oviduct recanalization by hysteroscopy combined surgery. A simple random method was used to divide into 2 groups, the control group was given conventional treatment, and the observation group was given conventional treatment+Wenjing Tongbaoyin treatment. The treatment effect, oviduct patency, pregnancy, adverse reactions and inflammatory indexs and hemorheology indexs before and after treatment were compared between the two groups. RESULTS The effective rate of treatment in the two groups was 66.67% and 93.94%, respectively, and the effective rate in the observation group was higher than that in the control group(P<0.05). There was a statistically significant difference between the two groups after treatment of the fallopian tube patency(P<0.05). The observation group had a higher oviduct patency rate than the control group. The rate of intrauterine pregnancy in the observation group was higher than that in the control group, and the rate of infertility was lower than that in the control group(P<0.05); there was no statistical difference in the rate of ectopic pregnancy between the two groups. The levels of interleukin(IL-6), tumor necrosis factor-α(TNF-α), plasma viscosity, high shear whole blood viscosity and low shear whole blood viscosity after treatment in the two groups were lower than those before treatment(P<0.05); The levels of IL-6, TNF-α, plasma viscosity, high shear whole blood viscosity and low shear whole blood viscosity after treatment in the observation group were lower than those in the control group(P<0.05). No adverse reactions occurred during treatment in both groups. CONCLUSION The application of Wenjing Tongbaoyin combined with hysteroscopy in oviduct obstructive infertility can improve the therapeutic effect, increase the pregnancy rate and improve the body's inflammatory state and hemorheology. |
| Key words: oviduct obstructive infertility Wenjing Tongbaoyin therapeutic effect |
