| 引用本文: | 井亚江,黄建萍,王七龙,安佳,王祥,王育朋,张岗,彭亮,高静,王昌利,颜永刚*.基于熵权TOPSIS法和灰色关联度分析筛选桔梗最佳采收期[J].中国现代应用药学,2024,41(9):1229-1237. |
| JING Yajiang,HUANG Jianping,WANG Qilong,AN Jia,WANG Xiang,WANG Yupeng,ZHANG Gang,PENG Liang,GAO Jing,WANG Changli,YAN Yonggang*.Study on the Optimal Harvesting Period of Platycodonis Radix by Grey Correlation Method and TOPSIS Method Based on Entropy Weight Method[J].Chin J Mod Appl Pharm(中国现代应用药学),2024,41(9):1229-1237. |
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| 基于熵权TOPSIS法和灰色关联度分析筛选桔梗最佳采收期 |
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井亚江1, 黄建萍1, 王七龙1, 安佳1, 王祥1, 王育朋2, 张岗1, 彭亮1, 高静1, 王昌利1, 颜永刚*1
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1.陕西中医药大学，陕西省秦岭中草药应用开发工程技术研究中心/"秦药"研发重点实验室，陕西 咸阳 712046;2.陕西海天制药有限公司，陕西 咸阳 712000
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| 摘要: |
| 目的 完善桔梗药材质量评价方法，研究3年生桔梗药材不同采收期下药材质量差异，确定桔梗药材最佳采收期。方法 以桔梗药材浸出物、灰分、水分、折干率以及所含6种皂苷类活性成分含量作为质量评价的检测指标，借助数理统计学方法，对不同采收期桔梗药材之间的差异进行表征。并结合熵权法、灰色关联度分析、TOPSIS法3种数学模型对桔梗药材质量评价指标进行统计分析，获得不同采收期桔梗药材质量排名信息。结果 采收期是影响桔梗药材质量差异的重要因素，不同采收期下3年生桔梗药材质量评价指标之间差异明显。所增加的多指标检测完善了桔梗质量评价体系，增强了药材的“性-效”联系。结合质量评价模型结果显示，3年生桔梗以10月21日(霜降)前后采收的桔梗药材综合指数得分最高。结论 为保证桔梗药材质量，结合药材外观性状特征与药材物质基础综合考虑，确定以“霜降”节气前后作为3年生桔梗的最佳采收期。 |
| 关键词: 桔梗 质量评价 采收期 熵权法 灰色关联度与TOPSIS融合模型 |
| DOI：10.13748/j.cnki.issn1007-7693.20231105 |
| 分类号: |
| 基金项目:内蒙古自治区科技重大专项(2019ZD005)；陕西中医药大学“秦药”品质评价与资源开发学科创新团队项目(2019-QN01)；国家中医药管理局全国名老中医药专家传承工作室建设项目(国中医药人函[2019]41号)；陕西中医药管理局中青年科技骨干人才(2023-ZQNY-003) |
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| Study on the Optimal Harvesting Period of Platycodonis Radix by Grey Correlation Method and TOPSIS Method Based on Entropy Weight Method |
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JING Yajiang1, HUANG Jianping1, WANG Qilong1, AN Jia1, WANG Xiang1, WANG Yupeng2, ZHANG Gang1, PENG Liang1, GAO Jing1, WANG Changli1, YAN Yonggang*1
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1.Shaanxi Engineering Research Center for Application and Development of Chinese Medicine in Qinling Mountains/Key Laboratory of "Qin Medicine" Research and Development, Shaanxi University of Chinese Medicine, Xianyang 712046, China;2.Shaanxi Haitian Pharmaceutical Co., Ltd., Xianyang 712000, China
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| Abstract: |
| OBJECTIVE To improve the quality evaluation method of Platycodonis Radix, to study the differences in the quality of three-years-old Platycodonis Radix under different harvesting periods, and to determine the optimal harvesting period of Platycodonis Radix. METHODS The leachate, ash, moisture, refractive index and the content of six saponins were used as the quality evaluation indexes. The differences between the herbs of Platycodonis Radix at different harvesting periods were characterized with the help of mathematical and statistical methods. And link the entropy weight method, gray correlation analysis and TOPSIS method were combined to obtain the statistical analysis of the relevant indexes and the quality ranking information of the herbs in different harvesting periods. RESULTS There were significant differences between the quality evaluation indexes of three-years-old Platycodonis Radix at different harvesting periods. The added multi-indicator testing had improved the quality evaluation system of Platycodonis Radix and enhanced the "Drug properties-Effectiveness" linkage of the herbs. And the results of the comprehensive quality evaluation model showed that the herbs harvested around October 21 (Frost’s Descent) were ranked best in terms of comprehensive index. CONCLUSION In order to ensure the quality of Platycodonis Radix, the best harvesting period for three-years-old Platycodonis Radix is determined around the "Frost’s Descent" season, taking into account the characteristics of the herbs' appearance and the material basis of herbs. |
| Key words: Platycodonis Radix quality evaluation harvesting period entropy weight method gray correlation degree and TOPSIS fusion model |
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