| 引用本文: | 徐弋翀,张艺华,裴蕊,孟廷廷,袁弘,胡富强.儿童微粉包衣制剂技术研究进展[J].中国现代应用药学,2023,40(22):3090-3096. |
| XU Yichong,ZHANG Yihua,PEI Rui,MENG Tingting,YUAN Hong,HU Fuqiang.Research Progress on the Technology of Microparticle Coating Pediatric Formulations[J].Chin J Mod Appl Pharm(中国现代应用药学),2023,40(22):3090-3096. |
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| 儿童微粉包衣制剂技术研究进展 |
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徐弋翀1, 张艺华1, 裴蕊1, 孟廷廷1,2, 袁弘1,2, 胡富强1,2
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1.浙江大学药学院, 杭州 310058;2.浙江大学金华研究院, 浙江 金华 321000
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| 摘要: |
| 目前国内儿童专用口服制剂数量较少，儿童用成人药现象普遍，开发新型儿童专用制剂很有必要。微粉包衣制剂技术能掩盖药物不良味道，提高制剂的依从性和便利性，适用于开发儿童制剂。本文总结儿童微粉包衣制剂技术研究应用现状和发展前景，为微粉包衣技术在儿童口服制剂领域的应用提供参考。 |
| 关键词: 微粉包衣 掩味 肠溶 缓控释 儿童用药 |
| DOI：10.13748/j.cnki.issn1007-7693.20232560 |
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| Research Progress on the Technology of Microparticle Coating Pediatric Formulations |
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XU Yichong1, ZHANG Yihua1, PEI Rui1, MENG Tingting1,2, YUAN Hong1,2, HU Fuqiang1,2
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1.College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China;2.Jinghua Institute of Zhejiang University, Jinghua 321000, China
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| Abstract: |
| Currently, there is a limited range of specialized oral preparations available for children, and it is common to find adult medications being used for pediatric purposes. This indicates a need for the development of new formulations specifically designed for children. Microparticle coating technology shows promise in masking the unpleasant taste of drugs, improving compliance and convenience in administration. Therefore, it can be considered an ideal approach for developing pediatric preparations. This article summarizes the current research and application status and development prospects of children's micro powder coating technology, providing reference for the application of micro powder coating technology in the field of children's oral preparations. |
| Key words: microparticle coating taste masking enteric coated controlled release pediatric drugs |
