| 引用本文: | 初丽媛,沈泽方,周艳,卢锐敏,魏宣,杨天潼.基于文献计量的超说明书用药主题动态演化研究[J].中国现代应用药学,2023,40(18):2576-2583. |
| CHU Liyuan,SHEN Zefang,ZHOU Yan,LU Ruimin,WEI Xuan,YANG Tiantong.Bibliometric Analysis of Off-label Drug Use in Dynamic Themes Evolution[J].Chin J Mod Appl Pharm(中国现代应用药学),2023,40(18):2576-2583. |
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| 基于文献计量的超说明书用药主题动态演化研究 |
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初丽媛1,2, 沈泽方2, 周艳1, 卢锐敏2,3, 魏宣2, 杨天潼2
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1.乐山职业技术学院, 四川 乐山 614000;2.中国政法大学证据科学研究院, 北京 100088;3.中国科学院大学深圳医院(光明), 广东 深圳 518000
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| 摘要: |
| 目的 从宏观角度对超说明书用药主题的动态演化过程展开全面的研究，以揭示该领域的整体发展脉络，发现该领域的研究热点和发展趋势。方法 以Web of Science中2012—2022年发表的以超说明书用药为主题的3 876篇文献为研究对象，运用SciMAT分析得到主题覆盖图、演化路径图和战略坐标图3个可视化图谱，并且对各时期的路径演化图和战略坐标图进行分析。结果 近十年来，超说明书用药的发文、主题和关键词数量不断增多，前一时期的研究主题对后一时期的影响较大，演化路径复杂，演化主题不断增加。大致在青少年及儿童、治疗、超说明书使用、药物-随机对照试验4个研究方向上形成了14条演化路径。结论 超说明书用药领域的研究内容和研究范围呈多元化发展，儿科用药、精神系统用药、COVID-19、准则等内容将得到更多的关注。 |
| 关键词: 超说明书用药 主题演化 聚类分析 SciMAT |
| DOI：10.13748/j.cnki.issn1007-7693.20222402 |
| 分类号:R969.3 |
| 基金项目:乐山市重点科技计划项目（22ZRKX020） |
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| Bibliometric Analysis of Off-label Drug Use in Dynamic Themes Evolution |
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CHU Liyuan1,2, SHEN Zefang2, ZHOU Yan1, LU Ruimin2,3, WEI Xuan2, YANG Tiantong2
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1.Leshan Vocational and Technical College, Leshan 614000, China;2.Institute of Evidence Law and Forensic Science, China University of Political Science and Law, Beijing 100088, China;3.Shenzhen Hospital of Chinese Academy of Sciences(Guangming), Shenzhen 518000, China
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| Abstract: |
| OBJECTIVE To study of the dynamic evolution process of the themes of off-label drug use from a macroscopic perspective, perspective is needed to reveal the overall development vein of the field, and discover research hot spots and development trends of the field. METHODS A total of 3 876 literatures published in Web of Science from 2012 to 2022 on the topic of off-label drug use were used to obtain three visual maps of overlapping map, systematic evolution map and strategic map by using SciMAT analysis, and these maps of each period were analyzed. RESULTS Over the past ten years, there had been an increasing in the number of publications, themes, and keywords on the off-label drug use, with research themes from the former period having a large impact on the latter period, with complex evolutionary pathways and increasing evolutionary themes. Roughly, 14 evolutionary paths were formed in 4 research directions:adolescents and children, treatment, off label use, and drug RCT. CONCLUSION The content and scope of research in the field of off-label drug use will be diversified and developed, with greater focus on pediatric drug use, psychiatric drug use, COVID-19, and guidelines will be paid more attention. |
| Key words: off-label drug use theme evolution cluster analysis SciMAT |
