| 引用本文: | 金鑫,付尧,张艳莉.专利视角下全球钠-葡萄糖共转运蛋白2抑制剂研究现状分析[J].中国现代应用药学,2023,40(7):976-981. |
| JIN Xin,FU Yao,ZHANG Yanli.Research Progress Analysis on the Sodium-glucose Co-transporter 2 Inhibitors from the Perspective of Global Patent[J].Chin J Mod Appl Pharm(中国现代应用药学),2023,40(7):976-981. |
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| 摘要: |
| 目的 梳理全球钠-葡萄糖共转运蛋白2(sodium-glucose co-transporter,SGLT2)抑制剂相关专利的现状,探讨该领域技术的研究布局及发展趋势,为国内同行提供参考借鉴。方法 以全球SGLT2抑制剂相关专利为研究对象,通过Incopat数据平台对其进行计量学统计和分析。结果与结论 SGLT2抑制剂相关技术专利于2014年后开始迅速增加,现已进入平稳发展阶段。分类号A61K、A61P、C07D的专利申请相对活跃,全球热点主题分布在医用配置、化合物或药物制剂的特定治疗活性等方向,头部研发机构主要聚焦在关键中间体、半水合物、协同转运蛋白、心力衰竭等聚类关键词方面。 |
| 关键词: 钠-葡萄糖共转运蛋白2 抑制剂 专利布局 专利分析 |
| DOI：10.13748/j.cnki.issn1007-7693.20222000 |
| 分类号:R977.1+5 |
| 基金项目: |
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| Research Progress Analysis on the Sodium-glucose Co-transporter 2 Inhibitors from the Perspective of Global Patent |
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JIN Xin1, FU Yao2, ZHANG Yanli1
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1.Jilin University, Changchun 130021, China;2.Department of Critical Care Medicine, The First Hospital of Jilin University, Changchun 130021, China
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| Abstract: |
| OBJECTIVE To comb the current status of patents related to sodium-glucose co-transporter(SGLT2) in the world, and explore the research layout and development trend, to provide reference for domestic peers. METHODS Took the global SGLT-2 patents as the research object, and conduct metrological statistics and analysis based on the Incopat patent data. RESULTS & CONCLUSION SGLT2 inhibitor patents began to increase rapidly since 2014, and entered a steady stage now. A61K, A61P, C07D patent applications were relatively active, global topics were distributed in the direction of medical configuration, specific therapeutic activity of compounds or pharmaceutical preparations, etc. The head R&D institutions mainly focused on key intermediates, hemihydrate, cotransporters, heart failure and other clustering keywords. |
| Key words: SGLT2 inhibitor patent layout patent analysis |
