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引用本文:王冉,包红霞.肠道菌群代谢产物与宿主疾病[J].中国现代应用药学,2020,37(23):2936-2944.
WANG Ran,BAO Hongxia.Metabolites of Intestinal Flora and Host Diseases[J].Chin J Mod Appl Pharm(中国现代应用药学),2020,37(23):2936-2944.
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肠道菌群代谢产物与宿主疾病
王冉, 包红霞
哈尔滨医科大学, 哈尔滨 150000
摘要:
研究发现人体中的肠道菌群在各种疾病的发生和发展中扮演着重要的角色,被认为是人体的“第9大系统”“第2基因组”。肠道菌群及其代谢产物直接影响着人体的健康。本文综述肠道菌群代谢产物与糖尿病、高血脂、免疫系统、结肠癌及心血管疾病的相关性及其潜在的作用机制。
关键词:  肠道菌群  肠道菌群代谢产物  短链脂肪酸  胆汁酸  氧化三甲胺
DOI:10.13748/j.cnki.issn1007-7693.2020.23.022
分类号:R963
基金项目:
Metabolites of Intestinal Flora and Host Diseases
WANG Ran, BAO Hongxia
Harbin Medical University, Harbin 150000, China
Abstract:
It has been found that the intestinal flora in the human body plays an important role in the emergence and development of various diseases which is considered to be “the ninth system” and “the second genome” of the body. Intestinal flora and its metabolites directly affect human health. This article focuses on the interaction between intestinal flora metabolites and diabetes, hyperlipidemia, immune system, colon cancer, cardiovascular diseases and its potential mechanisms.
Key words:  intestinal flora  metabolites of intestinal flora  short-chain fatty acid  bile acid  trimethylamine oxide
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