| 引用本文: | 潘斌,殷慧清,韦萍,韩世清*.4-噻唑酮类化合物的结构及其药理学活性研究[J].中国现代应用药学,2010,27(7):607-612. |
| .Study of the Structure and Pharmacological Activity of 4-Thiazolidinones[J].Chin J Mod Appl Pharm(中国现代应用药学),2010,27(7):607-612. |
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| 摘要: |
| 4-噻唑酮化合物是一类药理学活性广泛的化合物。本文简要介绍对于此类化合物的结构和活性研究。讨论了此类化合物抗菌活性、抗炎活性、抗癌活性等方面的研究进展，阐述了其在药物化学设计合成中的重要作用。 |
| 关键词: 4-噻唑酮 药理学活性 结构 构效关系 |
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| Study of the Structure and Pharmacological Activity of 4-Thiazolidinones |
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PAN Bin YIN Huiqing WEI Ping HAN Shiqing*
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| Abstract: |
| Because of the broad and potent activity, 4-thiazolidinones has established as one of the biologically important scaffolds. The recent progresses on the antibacterial, antibiofilm, antiinflammatory and anticancer activities of 4-thiazolidinones have been discussed in this paper. And the importance of the 4-thiazolidinones in medicinal chemistry is represented. |
| Key words: 4- thiazolidinone pharmacological activity structure structure-activity relationship |
