| 引用本文: | 肖律,钟强,谢娇,黄乐松,卢潇潇.385例药物不良反应报告分析[J].中国现代应用药学,2010,27(2):181-184. |
| .Analysis on Monitoring Reports of 385 Cases of Adverse Drug Reactions[J].Chin J Mod Appl Pharm(中国现代应用药学),2010,27(2):181-184. |
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| 摘要: |
| 目的 分析本院药品不良反应发生情况，促进医院合理用药。方法 对本院2007—2008年上报的385例不良反应病例进行回顾性分析。结果 引起不良反应发生的药品涉及广泛，发生率在前三位的是抗微生物药，中药制剂，调节水、电解质平衡药。其中静脉给药引发的不良反应例数为322例，占总不良反应例数的83.6％。不良反应临床表现主要是对皮肤、附件，消化系统，中枢神经系统，呼吸系统等的损害。结论 应该重视药物不良反应，加强监测工作。 |
| 关键词: 药物不良反应 监测 分析 |
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| Analysis on Monitoring Reports of 385 Cases of Adverse Drug Reactions |
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XIAO Lü ZHONG Qiang XIE Jiao HUANG Lesong LU Xiaoxiao
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| Abstract: |
| OBJECTIVE To analyze the incidence of adverse drug reactions(ADRs) in our hospital and promote rational use of drug. METHODS Three hundred and eighty-five cases of ADRs reported in 2007—2008 were analyzed retrospectively in our hospital. RESULTS Incidence of ADRs were associated with a wide range of drugs, the top three of drugs were anti-microbial drugs, traditional Chinese medicine preparations, regulating water and electrolyte balance in medicine. Three hundred and twenty-two cases of ADRs were caused by intravenous administration and the proportion of the total number of ADRs were 83.6%. The main clinical manifestations of ADRs were the damage of the skin or its annexes, the digestive system, central nervous system, respiratory system, and so on. CONCLUSION It should be paid great attention to ADRs and strengthen monitoring the incidence of ADRs. |
| Key words: adverse drug reactions monitor analysis |
