| 引用本文: | 洪清,袁曦,林功舟,陈庆伟.综合评分法优选天宁滴丸提取工艺[J].中国现代应用药学,2010,27(1):27-29. |
| .Optimization of Extraction Technology for Tianning Drop Pill by Colligation Score[J].Chin J Mod Appl Pharm(中国现代应用药学),2010,27(1):27-29. |
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| 摘要: |
| 目的 优选天宁滴丸最佳提取工艺。方法 采用L9 (34)正交试验，以天麻素、阿魏酸含量及浸膏得率的综合评分值为指标，对乙醇浓度、乙醇用量、回流时间、提取次数等因素进行考察。 结果 最佳提取工艺为加10倍量70%乙醇，回流3次，每次1 h。结论 该工艺合理，为工业化生产提供了科学依据。 |
| 关键词: 天宁滴丸 提取工艺 正交试验 |
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| Optimization of Extraction Technology for Tianning Drop Pill by Colligation Score |
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HONG Qing1 YUAN Xi1 LIN Gongzhou1 CHEN Qingwei2
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| Abstract: |
| OBJECTIVE To optimize the extraction technology of Tianning drop pill. METHODS The L9(34) orthogonal design was adopted in the study. Take the content of gastrodin and ferulic acid and yield of extract as index, to optimize the following factors in the extraction technology: ethanol concentration, amount of solvent, extraction time and extraction frequency. RESULTS The optimized condition was taken 70% ethanol as solvent, the best amount was 10 times of stuff solution, refluxed for three times and 1 hour for each time. CONCLUSION The optimized extraction technology is reasonable and provides scientific basis for industrialize process. |
| Key words: Tianning drop pill extraction technology orthogonal test |
