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摘要: |
目的了解超声波介导的药物靶向转运的研究情况。方法通过查阅和分析近年来国外超声波介导的药物转运文献。结果在超声波的作用下,药物能在体内特定部位释放药物,提高药物的局部浓度,以及治疗基因在细胞内的表达,亦增加药物的经皮渗透量。结论超声波具有良好的促进药物经皮吸收和靶向转运作用,具有一定的研究和应用前景。 |
关键词: 超声波 靶向药物转运 经皮渗透 |
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Ultrsonic-mediated Drug Delivery System |
ZHANG Qixiang
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Abstract: |
OBJECTIVE To introduce the update of ultrasonic-mediated drug delivery system. METHODS The relevant publications released overseas in recent years were referred and analyzed. RESULTS Ultrasonic can improve the transdermal drug delivery, induce targeted drug release in vivo and enhance local gene expression. CONCLUSION Ultrasonic has been demonstrated and it is a useful approach to facilitate both the transdermal drug delivery and the drug targeting. |
Key words: Ultrasonic-mediated targeted drug delivery transdermal drug delivery |