| 引用本文: | 王倩1,2;常湛1;李娟1;张挺3;王瑞英1;吴文成1.优甲乐对甲状腺功能减退症大鼠心肌损伤中Caspase-3和Bcl-2表达的影响[J].中国现代应用药学,2008,(6):482-487. |
| WANG Qian1,2,CHANG Zhan1,LI Juan1,ZHANG Ting3,WANG Rui-ying1,WU Wen-cheng1.Effects of Caspase-3 and Bcl-2 in Myocardial Cell in Hypothyroidism Rats and the Influence after Levothyroxine Sodium Intervention[J].Chin J Mod Appl Pharm(中国现代应用药学),2008,(6):482-487. |
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| 摘要: |
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| 关键词: 甲状腺功能减退症 心肌损伤 细胞凋亡 Caspase-3 Bcl-2 缺口末端标记法 左甲状腺素钠 |
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| 基金项目:河北省科技厅科技攻关项目(项目编号:06276102D-106) |
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| Effects of Caspase-3 and Bcl-2 in Myocardial Cell in Hypothyroidism Rats and the Influence after Levothyroxine Sodium Intervention |
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WANG Qian1,2,CHANG Zhan1,LI Juan1,ZHANG Ting3,WANG Rui-ying1,WU Wen-cheng1
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| Abstract: |
| OBJECTIVE To study the expression of the effecter molecule of myocardial cell apoptosis(Caspase-3) and the resisting apoptosis protein(Bcl-2) in hypothyroidism rats revealed the pathology of occurrence and development of the myocardial injury in hypothyro |
| Key words: hypothyroidism the myocardial injury apoptosis Caspase-3 Bcl-2 Termind deoxynudeotidy transferase mediated dTUP nick end labeling levothyroxine sodium |
