| 引用本文: | 张小林1;胡延雷2;高艳2;李征3.抗癌药物莱菔子素的合成[J].中国现代应用药学,2008,(4):312-313. |
| ZHANG Xiao-lin1,HU Yan-lei2,GAO Yan2,LI Zheng3.Synthesis of Sulforaphane[J].Chin J Mod Appl Pharm(中国现代应用药学),2008,(4):312-313. |
|
|
| 摘要: |
| 目的设计新的合成路线制备莱菔子素。方法以亚甲砜为原料经过三步反应合成莱菔子素。结果与结论目标产物的化学结构经红外光谱、核磁共振氢谱确证,该合成方法原料易得,操作简便,总收率为51.1%。 |
| 关键词: 药物化学 化学合成 莱菔子素 |
| DOI： |
| 分类号: |
| 基金项目:丰城鸡血藤抗乳腺癌黄酮类活性成分分离鉴定与化学修饰研究(2056008) |
|
| Synthesis of Sulforaphane |
|
ZHANG Xiao-lin1,HU Yan-lei2,GAO Yan2,LI Zheng3
|
| Abstract: |
| OBJECTIVE To design a new route to prepare sulforaphane.METHODS The target compound was synthesized from DMSO by three steps.RESULTS and CONCLUSION The structure of target compound was confirmed by IR,1HNMR,MS and the total yield was 51.1%.This procedure |
| Key words: medicinal chemistry synthesis sulforaphane |
