| 引用本文: | 陈志卫;闫伟华;苏为科.3-(2′-氯-6′-氟苯基)-5-甲基-4-异噁唑甲酰氯的合成[J].中国现代应用药学,2008,(4):308-309. |
| CHEN Zhi-wei,YAN Wei-hua,SU Wei-ke.Synthesis of 3-(2′-Chloro-6′-fluorophenyl)-5-methylisoxazole-4-carbonyl Chloride[J].Chin J Mod Appl Pharm(中国现代应用药学),2008,(4):308-309. |
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| 摘要: |
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| 关键词: 氟氯西林钠 3-(2′-氯-6′-氟苯基)-5-甲基-4-异噁唑甲酰氯 合成 |
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| 基金项目:浙江省科技厅资助项目(2005C24013) |
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| Synthesis of 3-(2′-Chloro-6′-fluorophenyl)-5-methylisoxazole-4-carbonyl Chloride |
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CHEN Zhi-wei,YAN Wei-hua,SU Wei-ke
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| Abstract: |
| OBJECTIVE To study the synthetic method of 3-(2-Chloro-6-fluoro phenyl)-5-methylisoxazole-4-carbonyl chloride.METHODS The objective compound was synthesized by steps of oximation,chlorination,cyclization,hydrolysis,acyl chlorination,starting from 2-chloro |
| Key words: Flucloxacillin 3-(2-Chloro-6-fluorophenyl)-5-methylisoxazole-4-carbonyl chloride synthesis |
