| 引用本文: | 刘学红1;郭瑞臣2;王本杰2.胺碘酮活性代谢物去乙基胺碘酮的生物制备及定量分析[J].中国现代应用药学,2006,(5):396-399. |
| LIU Xue-hong~(1),GUO Rui-chen~(2),WANG Ben-jie~(2).Preparation and quantification of desethylamiodarone[J].Chin J Mod Appl Pharm(中国现代应用药学),2006,(5):396-399. |
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| 摘要: |
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| 关键词: 胺碘酮 去乙基胺碘酮 高效液相色谱法 液相色谱-质谱法 定量 制备 |
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| Preparation and quantification of desethylamiodarone |
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LIU Xue-hong~(1),GUO Rui-chen~(2),WANG Ben-jie~(2)
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| Abstract: |
| OBJECTIVE To establish a method for the indirect quantification of desethylamiodarone with amiodarone as a standard by HPLC and to isolate and purify desethylamiodarone from tissues of amiodarone fed-dog with preparation-HPLC column.METHODS The selected g |
| Key words: amiodarone desethylamiodarone high performance liquid chromatography(HPLC) HPLC-MS quantification preparation |
