用不对称双羟化反应合成紫杉醇手性中间体(2R,3S)-2-3-二羟基-3-苯基丙酸乙酯

陈惠;金瑛;王巧峰;孙晓莉

引用本文:	陈惠;金瑛;王巧峰;孙晓莉.用不对称双羟化反应合成紫杉醇手性中间体(2R,3S)-2-3-二羟基-3-苯基丙酸乙酯[J].中国现代应用药学,2006,(4):299-301.
	CHEN Hui,JIN Ying,WANG Qiao-feng,SUN Xiao-li.Preparation of ethyl(2R,3S)-dihydroxy-3-phenylpropinate as intermediate of taxoi by asymmetric dihydroxylation reaction[J].Chin J Mod Appl Pharm(中国现代应用药学),2006,(4):299-301.

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用不对称双羟化反应合成紫杉醇手性中间体(2R,3S)-2-3-二羟基-3-苯基丙酸乙酯
陈惠;金瑛;王巧峰;孙晓莉

作者	单位
陈惠;金瑛;王巧峰;孙晓莉

摘要:

关键词: 手性配体不对称双羟化反应(AD) 紫杉醇C13片段

DOI：

分类号:

基金项目:国家自然科学基金资助(20272082,20302014)

Preparation of ethyl(2R,3S)-dihydroxy-3-phenylpropinate as intermediate of taxoi by asymmetric dihydroxylation reaction

CHEN Hui,JIN Ying,WANG Qiao-feng,SUN Xiao-li

Abstract:

OBJECTIVE To synthesize a cheap ligand and determine it's catalytic activities in asymmetric dihydroxylation(AD)reaction and to get ethyl-(2R,3S)-dihydroxy-3-phenylpropionate with high yield and enantioselectivity.METHODS The new chiral ligand (QN)2PYDZ w

Key words: chiral ligand asymmetric dihydroxylation(AD) C13 side chain oftaxol