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关键词: 肽类 蛋白质 肺部给药 体内外评价 |
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In vivo and in vitro evaluation of pulmonary drug delivery of proteins and peptides |
SHI Hui,JIANG Zhi-qiang
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Abstract: |
OBJECTIVE To introduce the in vivo and in vitro evaluation methods of pulmonary delivery of proteins and peptides.METHODS The drug delivery method,pharmacokinetic and pharmacodynamic evaluation,pulmonary deposition,in vitro evaluation and safety concerns |
Key words: peptide protein pulmonary delivery in vivo and in vitro evaluation |