针对PLK1基因mRNA的SiRNA治疗结肠癌的细胞学研究

符芳芳; 陈功星; 张家炜; 郑树; 丁佳逸

引用本文:	符芳芳，陈功星，张家炜，郑树，丁佳逸.针对PLK1基因mRNA的SiRNA治疗结肠癌的细胞学研究[J].中国现代应用药学,2005,(8):699-701.
	FU Fang-fang, CHEN Gong-xing, ZHANG Jia-wei, ZHENG Shu, DING Jia-yi.Cytological study about SiRNA to PLK1 mRNA on colorectal cancer therapy[J].Chin J Mod Appl Pharm(中国现代应用药学),2005,(8):699-701.

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针对PLK1基因mRNA的SiRNA治疗结肠癌的细胞学研究
符芳芳，陈功星，张家炜，郑树，丁佳逸

作者	单位
符芳芳，陈功星，张家炜，郑树，丁佳逸

摘要:

关键词: SiRNA PLK1 细胞存活细胞凋亡

DOI：

分类号:

基金项目:国家自然科学基金资助(30471943)

Cytological study about SiRNA to PLK1 mRNA on colorectal cancer therapy

FU Fang-fang, CHEN Gong-xing, ZHANG Jia-wei, ZHENG Shu, DING Jia-yi

Abstract:

OBJECTIVETo study the survival and growth of colorectal cell line SW480 treated by small interfering RNA (SiRNA) that aims to PLK1 (Polo-like kinase 1) mRNA. METHODSThree chemically synthesized SiRNA molecules were designed targeting different sites of PL

Key words: SiRNA PLK1 cell survival apoptosis