水/有机相两相体系中Saccharomyces cerevisiae B5不对称还原制备手性药物中间体R-2'-氯-1-苯乙醇的研究

欧志敏1*; 吴坚平2; 杨立荣2; 岑沛霖2

引用本文:	欧志敏1*,吴坚平2,杨立荣2,岑沛霖2.水/有机相两相体系中Saccharomyces cerevisiae B5不对称还原制备手性药物中间体R-2'-氯-1-苯乙醇的研究[J].中国现代应用药学,2004,(8):40-42.
	Ou Zhi-min1， Wu Jian-ping2， Yang Li-rong2，Cen Pei-lin2.Preparation of chiral pharmaceutical intermediate R-2'-chloro-1-phenyl-ethanol with the method of Saccharomyces cerevisiae B5 asymmetric reduction in water/organic diphasic system[J].Chin J Mod Appl Pharm(中国现代应用药学),2004,(8):40-42.

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水/有机相两相体系中Saccharomyces cerevisiae B5不对称还原制备手性药物中间体R-2'-氯-1-苯乙醇的研究
欧志敏1*,吴坚平2,杨立荣2,岑沛霖2

作者	单位
欧志敏1*,吴坚平2,杨立荣2,岑沛霖2

摘要:

关键词: 水/有机相两相体系 Saccharomyces cerevisiae B5 不对称还原手性药物中间体 R-2'-氯-1-苯乙醇

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Preparation of chiral pharmaceutical intermediate R-2'-chloro-1-phenyl-ethanol with the method of Saccharomyces cerevisiae B5 asymmetric reduction in water/organic diphasic system

Ou Zhi-min1， Wu Jian-ping2， Yang Li-rong2，Cen Pei-lin2

Abstract:

The process of preparation of chiral pharmaceutical intermediate R-2'-chloro-1-phenyl-ethanol with the method of Saccharomyces cerevisiae B5 asymmetric reduction in water/organic diphasic system was investigated in detail. The result shows that the higher

Key words: water/organic diphasic system Saccharomyces cerevisiae B5 asymmetric reduction chiral pharmaceutical intermediate R-2'-chloro-1-phenyl-ethanol