| 引用本文: | 褚良银，梁毅坚，王海东，李艳，陈文梅.葡萄糖浓度感应型胰岛素控制释放膜研究[J].中国现代应用药学,2004,(8):1-6. |
| CHU Liang-yin, LIANG Yi-jian, WANG Hai-dong, LI Yan, CHEN Wen-mei.Research on the glucose-responsive gating membranes for controlled insulin delivery[J].Chin J Mod Appl Pharm(中国现代应用药学),2004,(8):1-6. |
|
|
| 摘要: |
|
| 关键词: 葡萄糖感应 胰岛素释放 智能化给药系统；开关膜 开关特性 |
| DOI： |
| 分类号: |
| 基金项目:国家自然科学基金(20206019)、教育部跨世纪优秀人才培养计划基金、教育部留学回国人员科研基金和四川省杰出青年学科带头人培养基金（03ZQ026-41）资助项目。 |
|
| Research on the glucose-responsive gating membranes for controlled insulin delivery |
|
CHU Liang-yin, LIANG Yi-jian, WANG Hai-dong, LI Yan, CHEN Wen-mei
|
| Abstract: |
| The pore size and permeability control of a glucose-responsive gating membrane with plasma-grafted poly(acrylic acid) (PAAC) gates and covalently bound glucose oxidase (GOD) enzymes were investigated systematically. The PAAC-grafted porous polyvinylidene |
| Key words: Glucose-responsive Insulin release Intelligent drug delivery system Gating membrane Gating characteristics |
