以磺酰化β-环糊精为手性选择剂高效毛细管电泳拆分手性药物中间体

崔宏杰1; 2;吉爱国2;李从发3

引用本文:	崔宏杰1,2;吉爱国2;李从发3.以磺酰化β-环糊精为手性选择剂高效毛细管电泳拆分手性药物中间体[J].中国现代应用药学,2004,(3):188-190.
	CUI Hong-jie, JI Ai-guo, LI Cong-fa.High performance capillary electrophoresis separation of chiral drug intermediates with sulfated-β-cyclodextrin as chiral selector[J].Chin J Mod Appl Pharm(中国现代应用药学),2004,(3):188-190.

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以磺酰化β-环糊精为手性选择剂高效毛细管电泳拆分手性药物中间体
崔宏杰1,2;吉爱国2;李从发3

作者	单位
崔宏杰1,2;吉爱国2;李从发3

摘要:

关键词: 高效毛细管电泳磺酰化β-环糊精手性拆分

DOI：

分类号:

基金项目:山东省自然科学基金(No:Y2000C21);;教育部留学人员科研启动基金 (No:05200105)资助

High performance capillary electrophoresis separation of chiral drug intermediates with sulfated-β-cyclodextrin as chiral selector

CUI Hong-jie, JI Ai-guo, LI Cong-fa

Abstract:

OBJECTIVE To develop a method for the separation of the enantiomers of two chiral drug intermediates-phenylethanediol, styrene oxide by capillary electrophoresis. METHOD Phosphate-triethylamine buffer (pH 2.5) was used as the electrophoresis solution.

Key words: high performance capillary electrophoresis, sulfated-β-cyclodextrin, chiral separation