| 引用本文: | 张宣1;吴芳2;张志荣2.5-氨基水杨酸结肠定位释药包衣片在狗体内的靶向性研究[J].中国现代应用药学,2003,(4):288-289. |
| ZHANG Xuan 1, WU Fang 2 ,ZHANG Zhi-rong 2.Study on the colon targeting property of the 5-ASA colon-specific coated tablets[J].Chin J Mod Appl Pharm(中国现代应用药学),2003,(4):288-289. |
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| 摘要: |
| 目的 考察自制的口服5-氨基水杨酸结肠定位释药包衣片在体内的结肠靶向性。方法 用γ射线显影法考察结肠定位释放包衣片在狗体内的释药部位与释药时间。结果 5-氨基水杨酸结肠定位释药片剂在狗的升结肠崩解释药。结论 5-氨基水杨酸结肠定位释药片具有结肠靶向性。 |
| 关键词: 5-氨基水杨酸 结肠定位释药包衣片 靶向性 γ-射线显影法 |
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| 基金项目:国家杰出青年科学基金 (39925039);;卫生部科研基金资助项目 |
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| Study on the colon targeting property of the 5-ASA colon-specific coated tablets |
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ZHANG Xuan 1, WU Fang 2 ,ZHANG Zhi-rong 2
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| Abstract: |
| OBJECTIVE To investigate the colon targeting property of the self prepared 5-ASA colon specific coated tablets. METHOD The releasing site and time of the drug from the colon specific coated tablet in dogs were investigated by gamma scintigraphy usin |
| Key words: 5-aminosalicylic acid (5 ASA) colon specific coated tablets targeting property gamma scintigraphy |
