引用本文: | 杨敏;陈铁锋;余细勇;钱忆之;江桂芬;林曙光.阿替洛尔片人体相对生物利用度与生物等效性评价[J].中国现代应用药学,2003,(4):283-286. |
| YANG Min, CHEN Tie-feng, YU Xi-yong, QIAN Yi-zhi, JIANG Gui-fen, LIN Shu-guang.Evaluation for bioavailability and bioequivalence of atenolol in human[J].Chin J Mod Appl Pharm(中国现代应用药学),2003,(4):283-286. |
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关键词: 阿替洛尔 高效液相色谱法 相对生物利用度 生物等效性 |
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Evaluation for bioavailability and bioequivalence of atenolol in human |
YANG Min, CHEN Tie-feng, YU Xi-yong, QIAN Yi-zhi, JIANG Gui-fen, LIN Shu-guang
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Abstract: |
OBJECTIVE To study the difference in pharmacokinetices and relative bioavailability of atenolol produced by different factories. METHOD A single oral dose of 50 mg atenolol tablet was given respectively to 20 healthy volunteers in an open randomized cro |
Key words: atenolol HPLC relative bioavailability bioequivalent |