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关键词: 洛美利嗪 抗偏头痛 合成 |
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Synthesis of Lomerizine hydrochloride |
ZHOU Ping
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Abstract: |
OBJECTIVE To synthesize Lomerizine hydrochloride,a new drug for the treatment of antimigraine. METHOD Lomerizine hydrochloride was synthesized via Leuckart Wallach reaction.RESULTS The reaction was modified and improved,the yield was 56.9%.The struct |
Key words: lomerizine antimigraine synthesis |